| 类风关巴布剂中雷公藤甲素的提取方法研究 |
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| 引用本文： | 杨道纳. 类风关巴布剂中雷公藤甲素的提取方法研究[J]. 中国现代应用药学, 2012, 29(9): 811-813. |
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| 作者姓名： | 杨道纳 |
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| 作者单位： | 1.苍南县人民医院，浙江 苍南 325800 |
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| 摘 要： | 目的 研究并优化类风关巴布剂中雷公藤甲素的提取方法，并测定其含量。方法 HPLC测定类风关巴布剂中的雷公藤甲素含量，采用正交试验设计法考察甲醇浓度、甲醇体积、浸渍时间、提取时间对雷公藤甲素提取率的影响。结果 最佳提取条件为用100 mL的60%甲醇，浸渍4 h，加热回流2 h提取效率最高。结论 本方法为类风关巴布膏的质量控制提供了可靠的方法。
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| 关 键 词： | 类风关巴布剂 正交试验 雷公藤甲素 高效液相色谱法 |
| 收稿时间： | 2011-07-27 |
| 修稿时间： | 2012-08-27 |
Study on the Optimized Extraction Technology of Triptolide in Rhemeutoid-arthrosis Cataplasm |
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| YANG Daona. Study on the Optimized Extraction Technology of Triptolide in Rhemeutoid-arthrosis Cataplasm[J]. Chinese Journal of Modern Applied Pharmacy, 2012, 29(9): 811-813. |
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| Authors: | YANG Daona |
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| Affiliation: | 1.Cangnan People’s Hospital of Zhejiang Province, Cangnan 325800, China |
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| Abstract: | OBJECTIVE To study and optimize the extraction method of triptolide in rhemeutoid-arthrosis cataplasm. METHODS With the quantitative determination of triptolide in rhemeutoid-arthrosis cataplasm by HPLC method, orthogonal test was used to evaluate the extraction, factors including the methanol concentration, methanol volume, soaking time, extraction time. RESULTS The optimal condition was using 100 mL of 60% methanol, with soaking time of 4 h and refluxing time of 2 h. CONCLUSION The optimized method is reliable for the quality control of cataplasm. |
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| Keywords: | rhemeutoid-arthrosis cataplasm orthogonal test triptolide HPLC |
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