Sublethal concentrations of ciprofloxacin induce bacteriocin synthesis in Escherichia coli |
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| Authors: | Jerman Borut Butala Matej Zgur-Bertok Darja |
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| Affiliation: | Department of Biology, Biotechnical Faculty, University of Ljubljana, Vecna pot 111, Ljubljana, Slovenia. |
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| Abstract: | Antibiotics that interfere with DNA replication, as well as cell wall synthesis, induce the SOS response. In this report, we show that ciprofloxacin induces synthesis of colicins, narrow-spectrum antibiotics frequently produced by Escherichia coli strains, in an SOS-dependent manner. |
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