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术前多层螺旋CT增强扫描在老年非小细胞肺癌患者手术治疗中的应用价值
引用本文:李汝林, 张惠玲, 周德伟, 林志武, 樊建刚. 术前多层螺旋CT增强扫描在老年非小细胞肺癌患者手术治疗中的应用价值[J]. 分子影像学杂志, 2021, 44(6): 945-949. doi: 10.12122/j.issn.1674-4500.2021.06.12
作者姓名:李汝林  张惠玲  周德伟  林志武  樊建刚
作者单位:1.四川大学华西医院资阳医院//资阳市第一人民医院 胸心外科,四川 资阳 641303;2.四川大学华西医院资阳医院//资阳市第一人民医院 肿瘤科,四川 资阳 641303;3.四川大学华西医院资阳医院//资阳市第一人民医院 医学影像科,四川 资阳 641303
基金项目:四川省医学会课题2018SAT23
摘    要:目的  探究术前多层螺旋CT增强扫描在老年非小细胞肺癌(NSCLC)患者手术治疗中的应用价值。方法  回顾性分析2020年1月~2021年3月在本院接受治疗的120例老年NSCLC患者的临床资料,所有患者均接受多层螺旋CT增强扫描,分析多层螺旋CT诊断NSCLC的TNM分期、淋巴结转移与病理结果一致性,比较不同手术方式患者的手术情况和术后并发症发生情况。结果  术前多层螺旋CT增强扫描诊断T分期、N分期、淋巴结转移和临床分期的准确率分别为89.17%、90.83%、87.10%、88.33%,与病理结果一致性较高(Kappa=0.789、0.792、0.787、0.776)。120例NSCLC患者中,98例接受手术治疗,其中57例患者接受肺楔形切除术+淋巴结清扫术,41例患者接受全肺叶切除术+淋巴结清扫术;接受肺楔形切除术患者的手术时间明显短于接受全肺叶切除术的患者,术中出血量和淋巴结清扫数量少于接受全肺叶切除术的患者,并发症发生率发生率明显低于接受全肺叶切除术的患者(P < 0.05)。结论  多层螺旋CT增强扫描对老年NSCLC术前分期、淋巴结转移情况的诊断均具有较高准确度,可为手术方式的选择提供一定指导。

关 键 词:非小细胞肺癌   老年患者   多层螺旋CT   增强扫描   手术方式
收稿时间:2021-06-28

Application value of preoperative enhanced multi-slice spiral CT scan in the surgical treatment for elderly patients with non-small cell lung cancer
LI Rulin, ZHANG Huiling, ZHOU Dewei, LIN Zhiwu, FAN Jiangang. Application value of preoperative enhanced multi-slice spiral CT scan in the surgical treatment for elderly patients with non-small cell lung cancer[J]. Journal of Molecular Imaging, 2021, 44(6): 945-949. doi: 10.12122/j.issn.1674-4500.2021.06.12
Authors:LI Rulin  ZHANG Huiling  ZHOU Dewei  LIN Zhiwu  FAN Jiangang
Affiliation:1. Department of Cardio-Thoracic Surgery, The First People's Hospital of Ziyang, Ziyang 641303, China;2. Department of Oncology, The First People's Hospital of Ziyang, Ziyang 641303, China;3. Department of Medical Imaging, The First People's Hospital of Ziyang, Ziyang 641303, China
Abstract:  Objective  To explore the application value of preoperative enhanced multi-slice spiral CT scan in the surgical treatment for elderly patients with non-small cell lung cancer (NSCLC).  Methods  We retrospectively analyzed the clinical data of 120 elderly patients with NSCLC treated in the hospital between January 2020 and March 2021. All patients were subjected to enhanced multi- slice spiral CT scan. The consistency between multi- slice spiral CT and pathological results in diagnosing TNM stage and lymph node metastasis of NSCLC were analyzed. The operative conditions and postoperative complications of patients treated by different surgical methods were compared.  Results  The accuracy rates of preoperative enhanced multi-slice spiral CT scan in the diagnosis of T stage, N stage, lymph node metastasis and clinical stage were 89.17%, 90.83%, 87.10%, and 88.33%, which were consistent with pathological results (Kappa=0.789, 0.792, 0.787, 0.776). In the 120 patients with NSCLC, 98 received surgical treatment, including 57 patients undergoing pulmonary wedge resection and lymph node dissection, and 41 patients undergoing total lobectomy and lymph node dissection. The operation time of patients undergoing pulmonary wedge resection were significantly shorter than those of patients undergoing total lobectomy. The intraoperative blood loss and number of lymph nodes removed were less or smaller than those of patients undergoing total lobectomy, and the incidence of complications was significantly lower than that in patients undergoing total lobectomy (P < 0.05).  Conclusion  Enhanced multi- slice spiral CT scan has high accuracy in the diagnosis of preoperative stage and lymph node metastasis of NSCLC, thereby providing guidance for the selection of surgical methods. 
Keywords:non-small cell lung cancer  elderly patient  multi-slice spiral CT  enhanced scan  surgical method
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