| 运动干预对多发性硬化患者疲劳症状影响的Meta分析北大核心CSCD |
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| 引用本文： | 徐振,王一迪,张月,温宇红. 运动干预对多发性硬化患者疲劳症状影响的Meta分析北大核心CSCD[J]. 中国康复理论与实践, 2022, 28(5): 568-577. DOI: 10.3969/j.issn.1006-9771.2022.05.012 |
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| 作者姓名： | 徐振 王一迪 张月 温宇红 |
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| 作者单位： | 1.南开大学体育部,天津市 3000712.北京体育大学中国游泳运动学院,北京市 1000843.上海交通大学体育系,上海市 2002404.北京体育大学体育休闲与旅游学院,北京市 1000845.北京体育大学运动与体质健康教育部重点实验室,北京市 100084 |
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| 基金项目： | 国家重点研发计划项目(2020YFC2006700) |
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| 摘 要： | 目的评价运动干预对多发性硬化(MS)患者疲劳症状的影响及其安全性。方法计算机检索PubMed、Cochrane Central Register of Controlled Trails、Web of Science、中国知网和万方数据库,收集从建库至2021年6月发表的关于运动干预对MS疲劳影响的随机对照试验。由两名研究人员进行文献检索与筛选,并独立对纳入文献进行质量评价。采用Stata 16.0软件进行Meta分析。结果共纳入41项随机对照试验,共2155例患者。与对照组相比,运动干预能显著改善试验组疲劳症状(SMD=-0.59,95%CI-0.73~-0.44,P<0.001);随访期间试验组与对照组无显著性差异(SMD=-0.07,95%CI-0.26~0.12,P=0.47)。运动干预未增加复发风险(RR=0.67,95%CI 0.45~1.00,P=0.06)。结论运动干预能够有效减轻MS疲劳症状,且未造成MS复发率的升高。
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| 关 键 词： | 多发性硬化 运动 疲劳 Meta分析 |
| 收稿时间： | 2021-12-09 |
Effects of exercise intervention on fatigue for patients with multiple sclerosis: a meta-analysis |
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| XU Zhen,WANG Yidi,ZHANG Yue,WEN Yuhong. Effects of exercise intervention on fatigue for patients with multiple sclerosis: a meta-analysis[J]. Chinese Journal of Rehabilitation Theory and Practice, 2022, 28(5): 568-577. DOI: 10.3969/j.issn.1006-9771.2022.05.012 |
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| Authors: | XU Zhen WANG Yidi ZHANG Yue WEN Yuhong |
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| Affiliation: | 1. Department of Physical Education, Nankai University, Tianjin 300071, China2. China Swimming College, Beijing Sport University, Beijing 100084, China3. Department of Physical Education, Shanghai Jiao Tong University, Shanghai 200240, China4. School of Recreational Sports and Tourism, Beijing Sport University, Beijing 100084, China5. Key Laboratory of Sports and Physical Health of the Ministry of Education, Beijing Sport University, Beijing 100084, China |
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| Abstract: | Objective To evaluate the effect and safety of exercise intervention on fatigue for patients with multiple sclerosis (MS). Methods Randomized controlled trials (RCT) about effect of exercise intervention on MS fatigue were retrieved from the databases of PubMed, Cochrane Central Register of Controlled Trails, Web of Science, CNKI and Wanfang Data from establishment to June, 2021. Two researchers independently screened the literature, extracted the data and assessed the quality of eligible studies. Meta-analysis was performed with Stata 16.0. Results A total of 41 RCT with 2 155 patients were included. Compared with control group, exercise intervention might improve the MS fatigue at the end of intervention in exercise group (SMD = -0.59, 95%CI -0.73 to -0.44, P < 0.001). There was no significant difference between the exercise group and the control group in follow-up period (SMD = -0.07, 95%CI -0.26 to 0.12, P = 0.47). Exercise intervention did not increase the recurrence of MS (RR = 0.67, 95%CI 0.45 to 1.00, P = 0.06). Conclusion Exercise intervention can effectively relieve the fatigue of MS without increasing the recurrence of MS. |
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| Keywords: | multiple sclerosis exercise fatigue meta-analysis |
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