| 慢性牙周炎患者和健康者非刺激性全唾液中的差异蛋白比较 |
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| 引用本文： | Wu Y,Shu R,Liu H. 慢性牙周炎患者和健康者非刺激性全唾液中的差异蛋白比较[J]. 华西口腔医学杂志, 2011, 29(5): 519-521. DOI: 10.3969/j.issn.1000-1182.2011.05.018 |
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| 作者姓名： | Wu Y Shu R Liu H |
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| 作者单位： | 1.同济大学附属口腔医院牙周科, 上海200072;2.上海交通大学医学院附属第九人民医院牙周科, 上海200011 |
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| 摘 要： | 目的 比较慢性牙周炎患者和健康对照者非刺激性全唾液(WUS)中的差异表达蛋白.方法 采集5名慢性牙周炎患者和5名健康者的WUS,利用双向凝胶电泳(2-DE)分离蛋白,将二者之间的差异蛋白质点进行基质辅助激光解析电离串联飞行时间质谱鉴定.结果 通过软件对2组样品的双向胶上的点进行对比分析,发现17个差异点,经质谱鉴定明确...
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| 关 键 词： | 慢性牙周炎 非刺激性全唾液 差异蛋白 双向电泳 质谱 |
| 收稿时间： | 2011-10-25 |
| 修稿时间： | 2011-10-25 |
Comparison of proteomic profiles of whole unstimulated saliva obtained from generalized aggressive periodontitis patients and healthy controls |
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| Wu Ying,Shu Rong,Liu Hongwei. Comparison of proteomic profiles of whole unstimulated saliva obtained from generalized aggressive periodontitis patients and healthy controls[J]. West China journal of stomatology, 2011, 29(5): 519-521. DOI: 10.3969/j.issn.1000-1182.2011.05.018 |
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| Authors: | Wu Ying Shu Rong Liu Hongwei |
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| Affiliation: | 1. Dept. of Periodontology, The Affiliated Stomatology Hospital of Tongji University, Shanghai 200072, China; 2. Dept. of Periodontology, The Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, China |
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| Abstract: | Objective To compare the proteomic profiles of whole unstimulated saliva(WUS) of subjects with chronic periodontitis(CP) with that of healthy volunteers,and to identify proteins.Methods WUS was obtained from five subjects with CP and five healthy subjects,and proteins were separated using two-dimensional gel electrophoresis(2-DE). Proteins,the level of which was significantly different among the two groups,were identified by computer image analyses and subsequent matrix-assisted laser desorption/ionization ... |
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| Keywords: | chronic periodontitis whole unstimulated saliva differentiated protein two-dimensional gel electro-phoresis mass spectrometry |
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