| 保乳术、改良根治术和改良根治术联合放疗治疗三阴性乳腺癌术后局部复发情况比较 |
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| 引用本文： | 岳雁鸿,王瑶,曾燕. 保乳术、改良根治术和改良根治术联合放疗治疗三阴性乳腺癌术后局部复发情况比较[J]. 中华普外科手术学杂志(电子版), 2019, 13(2): 177-179. DOI: 10.3877/cma.j.issn.1674-3946.2019.02.021 |
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| 作者姓名： | 岳雁鸿 王瑶 曾燕 |
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| 作者单位： | 1. 620010 四川省眉山市中医医院普外科 |
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| 摘 要： | 目的探讨保乳术、改良根治术和保乳术联合放疗治疗三阴性乳腺癌的术后局部复发情况。 方法回顾性分析2009年1月至2014年12月间接受治疗的320例三阴乳腺癌患者资料，根据手术方案分为保乳术(BCT组)132例、改良根治术(MRM组)120例、保乳术联合放疗(联合组)68例。采用SPSS19.0软件进行统计分析。术中术后等计量资料采用( ±s)描述，组间比较采用单因素方差分析。采用COX生存回归分析术后3年的局部复发风险。P<0.05为差异有统计学意义。 结果三组的手术时间差异无统计学意义(P>0.05)，BCT组和联合组的切口长度、术中出血量和住院时间显著优于MRM(P<0.05)；术后3年，BCT组、MRM组的局部复发风险分别是联合组的2.37倍、2.24倍(P<0.05)；胸壁转移风险是联合组的3.14倍、3.85倍(P<0.05)；BCT组的淋巴结转移风险是联合组的2.65倍(P<0.05)，MRM组的淋巴结转移风险和联合组差异无统计学意义(P>0.05)。 结论相较于改良根治术，保乳术联合放疗治疗乳腺癌不仅能术后恢复快、降低局部复发风险，还能保证相对正常的乳房外形，有利于患者术后生存质量提高，具有临床价值。
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| 关 键 词： | 乳腺肿瘤 乳房切除术，区段 乳房切除术，改良根治性 放射疗法 肿瘤复发，局部 |
| 收稿时间： | 2018-05-06 |
Comparison of local recurrence for triple negative breast cancer after breast conserving therapy,modified radical mastectomy and breast conserving therapy combined with radiation therapy |
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| Yanhong Yue,Yao Wang,Yan Zeng. Comparison of local recurrence for triple negative breast cancer after breast conserving therapy,modified radical mastectomy and breast conserving therapy combined with radiation therapy[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Version, 2019, 13(2): 177-179. DOI: 10.3877/cma.j.issn.1674-3946.2019.02.021 |
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| Authors: | Yanhong Yue Yao Wang Yan Zeng |
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| Affiliation: | 1. Department of general surgery, Meishan city of traditional Chinese medicine, Meishan City, Sichuan Province, 620010 |
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| Abstract: | ObjectiveTo investigate the local recurrence of three negative breast cancer after breast conserving surgery, modified radical mastectomy and breast conserving therapy combined with radiotherapy. Methods320 cases of three negative breast cancer patients from January 2009 to December 2014 treated in our hospital were selected as the research object, according to the operation, they were divided into breast conserving surgery group(BCT), 132 cases, modified radical surgery group (MRM), 120 cases, breast conserving therapy combined with radiotherapy (BCT & RT) group, 68 cases. The general information of patients, surgery, hospitalization time between three groups were compared with one-way ANOVA and Pearson χ2 test, and the postoperative 3 years local recurrence risk was analyzed with Cox regression. ResultsNo significant difference in operation time of BCT group, MRM group, MRM and RT group was found (P>0.05), blood loss and hospitalization time, incision length of BCT were significantly better than those of MRM, (P<0.05); 3 years after surgery, the risk of local recurrence in BCT group and MRM group were 2.37 times, 2.24 times than in the BCT and RT group (P<0.05), chest wall metastasis risk is 3.14 times, 3.85 times than in the BCT and RT group (P<0.05); the risk of lymph node metastasis in BCT group is 2.65 times than in the BCT and RT group (P<0.05). Compared with MRM group, the risk of lymph node metastasis had no significant difference in BCT and RT group (P>0.05). ConclusionCompared with modified radical mastectomy, breast conserving surgery combined with radiation therapy for breast cancer can not only recover quickly, reduce the risk of local recurrence, but also ensure a relatively normal breast shape, which is conducive to the improvement of postoperative quality of life and has clinical value. |
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| Keywords: | Breast neoplasms Mastectomy segmental Mastectomy modified radical Radiotherapy Neoplasm recurrence local |
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