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腹膜后巨大脂肪肉瘤一例报告并文献复习
引用本文:郑建坤,黄展森,王德娟,黄文涛,李科,胡成,邱剑光. 腹膜后巨大脂肪肉瘤一例报告并文献复习[J]. 中华腔镜泌尿外科杂志(电子版), 2019, 13(4): 280-284. DOI: 10.3877/cma.j.issn.1674-3253.2019.04.016
作者姓名:郑建坤  黄展森  王德娟  黄文涛  李科  胡成  邱剑光
作者单位:1. 516211 广东,惠州市第六人民医院泌尿外科2. 510630 广州,中山大学附属第三医院不育与性医学科3. 510655 广州,中山大学附属第六医院泌尿外科4. 510630 广州,中山大学附属第三医院泌尿外科
基金项目:广东省自然基金(2017A030313898); 广东省科技计划(2017A020215028); 广州市科技计划(201707010113); 广州市珠江科技新星人才专项(201710010039); 中山大学青年教师培育项目(17ykpy48)
摘    要:目的探讨腹膜后巨大脂肪肉瘤术后腹腔复发患者多学科诊疗模式(MDT)。 方法回顾性分析腹膜后巨大脂肪肉瘤术后腹腔复发患者1例,男,45岁,复发肿瘤大小约10 cm×9 cm的临床病例资料及其两次诊治过程及MDT讨论要点分析,复习总结国内外相关文献。 结果患者行开放腹腔多发肿物切除+胆囊切除+大网膜切除术成功切除肿瘤,术后病理为去分化型脂肪内瘤。经治疗后恢复良好出院。一个半月后复发,继续靶向药物(阿帕替尼500 mg qd)治疗。 结论腹膜后脂肪肉瘤早期诊断困难,手术难度大,MDT及结合影像学检查及临床病理学特征可作出正确诊断,充分评估早期手术治疗可获得一定疗效,但去分化型脂肪内瘤总体预后不良。

关 键 词:脂肪肉瘤  腹腔肿物  手术  腹膜后  多科学诊疗模式  
收稿时间:2018-03-14

Huge retroperitoneal liposarcoma: one case report and literature review
Jiankun Zheng,Zhansen Huang,Dejuan Wang,Wentao Huang,Ke Li,Cheng Hu,Jianguang Qiu. Huge retroperitoneal liposarcoma: one case report and literature review[J]. , 2019, 13(4): 280-284. DOI: 10.3877/cma.j.issn.1674-3253.2019.04.016
Authors:Jiankun Zheng  Zhansen Huang  Dejuan Wang  Wentao Huang  Ke Li  Cheng Hu  Jianguang Qiu
Affiliation:1. Department of Urology, the Sixth People′s Hospital of Huizhou, Guangdong 516211, China2. Department of Infertility and Sexual Medicine, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China3. Department of Urology, the Sixth Affiliated Hospital of Sun Yat-Sen University , Guangzhou 510655, China4. Department of Urology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China
Abstract:ObjectiveTo explore the multi-disciplinary team (MDT) for patients with peritoneal tumor recurrence after surgical resection of retroperitoneal giant liposarcoma. MethodsClinical data of a 45-year-old male patient with peritoneal tumor recurrence approximately 10 cm×9 cm in size after surgical resection of retroperitoneal giant liposarcoma were retrospectively analyzed. The procedures of two cycles of diagnoses and treatments and MDT highlights were reviewed. Relevant literatures at home and abroad were summarized. ResultsThe patient underwent open resection of multiple abdominal tumors + cholecystectomy + omentectomy to successfully resect the tumors. Postoperative pathological examination confirmed the diagnosis of dedifferentiated lipoblastoma. The patient was recovered and discharged after treatment. At postoperative 45 d, the patient recurred and continued to be treated with targeted drugs (Apatinib at 500 mg qd). ConclusionIt is difficult to deliver early diagnosis of retroperitoneal liposarcoma and perform the operation. MDT combined with imaging examination and clinicopathological features can make an accurate diagnosis. Comprehensive evaluation of early surgery can achieve certain clinical efficacy, whereas the overall prognosis of patients with dedifferentiated liposarcoma is poor.
Keywords:Liposarcoma  Abdominal mass  Surgery  Etroperitoneal  MDT  
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