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球囊后凸椎体成形术对椎体转移癌患者疼痛缓解和功能恢复的作用
引用本文:朱建华,肖文华,孙玉鹏,郝怡鑫,王如良,李秋文,彭秀梅. 球囊后凸椎体成形术对椎体转移癌患者疼痛缓解和功能恢复的作用[J]. 中国肿瘤临床, 2012, 39(21): 1595-1597. DOI: 10.3969/j.issn.1000-8179.2012.21.005
作者姓名:朱建华  肖文华  孙玉鹏  郝怡鑫  王如良  李秋文  彭秀梅
作者单位:①.解放军总医院第一附属医院肿瘤科(北京市100048)
摘    要:  目的  观察经皮球囊后凸椎体成形术(PKP)在缓解椎体转移癌患者疼痛和功能恢复中的临床价值。  方法  28例椎体转移癌患者接受了PKP治疗。记录并比较患者手术前后止痛药物应用比例、疼痛程度、止痛药用量和活动能力。  结果  45个椎体的PKP手术均1次成功。术后1周13例(46.4%)患者疼痛完全缓解, 13例(46.4%)明显缓解。术后止痛药物应用比例、疼痛评分、活动能力评分较术前明显改善(P < 0.01)。  结论  PKP能快速缓解椎体转移瘤引起的疼痛, 增强病椎强度和稳定性, 预防病椎进一步压缩骨折, 具有简单、安全、有效等优点。 

关 键 词:经皮球囊椎体后凸成形术   脊柱转移癌   疼痛
收稿时间:2012-09-28

The Efficacy of Pain Relief and Function Restoration of Percutaneous Balloon Kyphoplasty for Vertebral Metastases
Jianhua ZHU,Wenhua XIAO,Yupeng SUN,Yixin HAO,Ruliang WANG,Qiuwen LI,Xiumei PENG. The Efficacy of Pain Relief and Function Restoration of Percutaneous Balloon Kyphoplasty for Vertebral Metastases[J]. Chinese Journal of Clinical Oncology, 2012, 39(21): 1595-1597. DOI: 10.3969/j.issn.1000-8179.2012.21.005
Authors:Jianhua ZHU  Wenhua XIAO  Yupeng SUN  Yixin HAO  Ruliang WANG  Qiuwen LI  Xiumei PENG
Affiliation:①.Department of Oncology, The First Affiliated Hospital of PLA General Hospital, Beijing 100048, China②.Department of Orthopedics, The First Affiliated Hospital of PLA General Hospital, Beijing 100048, China
Abstract:  Objective  To investigate the efficacy of pain relief and function restoration of Percutaneous Balloon kyphoplasty (PKP) for vertebral metastases.  Methods  This is an open-labeled prospective study. A total of 28 patients with vertebral metastases were treated with PKP. Pain intensity, dose of analgesics, activity ability of vertebra before and after the operations were recorded and evaluated.  Results  PKP was conducted in 45 vertebras successfuUy. At one week after operation, 13 patients (46.4%) had pain relief completely and 13 (46.4%) patients gained pain relief significantly. Analgesics dose, pain intensity, and activity ability of vertebra were significantly improved after the operation (P < 0.01).  Conclusion  PKP is a safe and effective measure to treat metastatic spinal tumor. It can release vertebral metastasis-related pain and enhance strength and stability of the abnormal vertebra. 
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