| 剪切波弹性成像所测胰腺硬度与2型糖尿病微血管病变的关系 |
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| 引用本文： | 马静丽,叶创文,朱贤胜. 剪切波弹性成像所测胰腺硬度与2型糖尿病微血管病变的关系[J]. 临床超声医学杂志, 2024, 26(7) |
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| 作者姓名： | 马静丽 叶创文 朱贤胜 |
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| 作者单位： | 中国人民解放军南部战区总医院 超声诊断科广东 广州,中国人民解放军南部战区总医院 超声诊断科广东 广州,中国人民解放军南部战区总医院 超声诊断科广东 广州 |
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| 摘 要： | 目的 基于超声弹性成像分析2型糖尿病(T2DM)患者胰腺改变,分析其与微血管病变的关系。方法 选取2022年1月-2023年2月本院T2DM患者200例纳入T2DM组,另外选取同期于本院进行健康体检者200例纳入对照组,所有纳入对象均先后通过二维常规超声观察胰腺大小形态与内部回声,采用剪切波弹性成像方法检测胰头、胰体和胰尾组织平均杨氏模量值(Emean),依照T2DM组患者微血管病变发生情况,分为合并微血管病变组(n=86)、未合并微血管病变组(n=114),通过受试者工作曲线(ROC)分析患者胰腺改变对微血管病变发生的评估。结果 T2DM组胰腺高回声比例高于对照组,胰头、胰体、胰尾厚径大于对照组(P＜0.05);胰腺超声弹性成像显示,T2DM组胰头、胰体、胰尾Emean值均高于对照组(P＜0.05);T2DM合并与未合并微血管病变患者胰腺回声增强以及胰头、胰体、胰尾厚径比较(P＞0.05);T2DM合并与未合并微血管病变患者胰腺超声弹性成像胰头与胰尾Emean值比较(P＞0.05);T2DM合并微血管病变组患者胰体Emean值高于未合并微血管病变组(P＜0.05);胰体Emean水平评估T2DM患者微血管病变发生ROC曲线下面积为0.758[95%CI(0.689-0.826)],灵敏度为74.42%,特异度为71.93%。结论 T2DM患者胰腺回声增强,胰腺体积增加,超声弹性成像结果显示胰头、胰体、胰尾硬度增加,且当T2DM合并微血管并发症时,胰体硬度增加明显。
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| 关 键 词： | 2型糖尿病 超声弹性成像 胰腺 微血管病变 |
| 收稿时间： | 2023-08-02 |
| 修稿时间： | 2024-03-19 |
Analysis of pancreatic changes and their relationship with microvascular lesions in patients with type 2 diabetes mellitus based on ultrasonic elastography |
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| Ma Jingli,Ye Chuangwen and Zhu Xiansheng. Analysis of pancreatic changes and their relationship with microvascular lesions in patients with type 2 diabetes mellitus based on ultrasonic elastography[J]. Journal of Ultrasound in Clinical Medicine, 2024, 26(7) |
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| Authors: | Ma Jingli Ye Chuangwen Zhu Xiansheng |
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| Affiliation: | Ultrasound Diagnosis Department,General Hospital of Southern Theater Command of PLAGuangzhou,Ultrasound Diagnosis Department,General Hospital of Southern Theater Command of PLAGuangzhou,Ultrasound Diagnosis Department,General Hospital of Southern Theater Command of PLAGuangzhou |
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| Abstract: | Objective To analyze the pancreatic changes in patients with type 2 diabetes mellitus (T2DM) based on ultrasonic elastography, and to analyze their relationship with microvascular lesions. Methods A total of 200 patients with T2DM and 200 healthy controls in the hospital were enrolled as T2DM group and control group between January 2022 and February 2023. The pancreatic size, morphology and internal echo were observed by routine two-dimensional ultrasound. The mean Youngs modulus (Emean) in pancreatic head, body and tail tissues were detected by shear wave elastography. According to the presence or absence of microvascular lesions, patients in T2DM group were divided into lesion group (n=86) and non-lesion group (n=114). The evaluation value of pancreatic changes for microvascular lesions was analyzed by receiver operating characteristic (ROC) curves. Results The proportion of pancreatic hyperecho in T2DM group was higher than that in control group, and diameters of pancreatic head, body and tail were longer than those in control group (P<0.05). Ultrasonic elastography showed that Emean values of pancreatic head, body and tail tissues in T2DM group were greater than those in control group (P<0.05). The difference in pancreatic echo enhancement and diameters of pancreatic head, body and tail between lesion group and non-lesion group was not statistically significant (P>0.05). The difference in Emean values of pancreatic head and tail tissues between lesion group and non-lesion group was not statistically significant (P>0.05). Emean of pancreatic body in lesion group was greater than that in non-lesion group (P<0.05). The area under ROC curve (AUC), sensitivity and specificity of Emean of pancreatic body for evaluating microvascular lesions were 0.758 [95%CI (0.689-0.826)], 74.42% and 71.93%, respectively. Conclusion In T2DM patients, pancreatic echo is enhanced and pancreatic volume is enlarged. Ultrasonic elastography shows that hardness of pancreatic head, body and tail is increased. The hardness of pancreatic body is increased significantly in T2DM patients with microvascular complications. |
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| Keywords: | Type 2 diabetes mellitus Ultrasonic elastography Pancreas Microvascular lesion |
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