| 鼻咽癌放疗对听性脑干功能的远期影响 |
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| 引用本文： | 吴湘萍. 鼻咽癌放疗对听性脑干功能的远期影响[J]. 山东大学耳鼻喉眼学报, 2007, 21(1): 46-47 |
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| 作者姓名： | 吴湘萍 |
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| 作者单位： | 湖南株洲恺德微创医院耳鼻喉科,湖南,株洲,412000 |
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| 摘 要： | 目的：探讨放射治疗对鼻咽癌患者听性脑干功能的远期影响。方法：对鼻咽癌33例(66耳)患者于放疗前，放疗后第1天及第3、6、12、24、36个月分别行听性脑干反应(ABR)检测。结果：放疗完成后第1天与放疗前对比，听性脑干无明显减退。听性脑干部分指标3个月后开始减退，6个月后全面减退。在6～12个月之间，听性脑干部分修复，但此后听性脑干呈缓慢减退的趋势。结论：常规的鼻咽癌放疗对患者近期听性脑干可能无明显影响，但会引起其远期的损伤，为了防止出现严重后果，必需早期采取积极的防治措施。
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| 关 键 词： | 诱发电位 听觉 脑干 鼻咽肿瘤 放射疗法 |
| 文章编号： | 1673-3770（2007）01-0046-02 |
| 收稿时间： | 2006-09-08 |
| 修稿时间： | 2006-09-082006-12-31 |
Long-term effect on auditory brain stem function of patients with nasopharyngeal carcinoma after radiotherapy |
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| WU Xiang-ping. Long-term effect on auditory brain stem function of patients with nasopharyngeal carcinoma after radiotherapy[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2007, 21(1): 46-47 |
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| Authors: | WU Xiang-ping |
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| Affiliation: | Department of Otolaryngology, Zhuzhou Kaide Hospital, Zhuzhou 412000, Hunan, China |
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| Abstract: | Objective： To investigate the long term effect of radiotherapy on auditory brain stem function of patients with nasopharyngeal carcinoma(NPC). Methods： The auditory brain stem response(ABR) was examined in 33 patients (66 ears) with NPC before and at the first day, and on 3, 6, 12, 24 and 36 months after radiotherapy. Results： There were no obvious harmon auditory functions at the first day after radiotherapy. The auditory function decreased significantly at 6 months after radiotherapy and slightly recovered in the next 6 months, but after that it slightly decreased again. Conclusions： Conventional radiotherapy harms the auditory function in the long term after treatment, so effective means should be adopted as early as possible. |
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| Keywords: | Evoked potentials, auditory, brain stem Nasopharyngeal neoplasms Radiotherapy |
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