Single‐fiber EMG with concentric electrodes in lambert‐eaton myasthenia |
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| Authors: | Yuzhou Guan MD Qingyun Ding BS Mingsheng Liu MD Jingwen Niu MD Liying Cui MD |
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| Affiliation: | Department of Neurology, Peking Union Medical College Hospital, Dongcheng, Beijing, China |
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| Abstract: | Introduction: We analyzed jitter recordings made with concentric needle electrode (CNE) single‐fiber electromyography (SFEMG) in Lambert‐Eaton myasthenia (LEM). Methods: Fifteen subjects diagnosed with LEM were studied using CNE‐SFEMG in the extensor digitorum (ED) and tibialis anterior (TA) muscles. CNE‐SFEMG in the ED and TA was also used to evaluate 12 and 10 healthy controls (HCs), respectively. Results: Ten men and 5 women were diagnosed with LEM based on an increase of 100% in compound muscle action potential amplitude during 50 Hz repetitive nerve stimulation. All patients exhibited markedly greater jitter in the ED (88.8 ± 23.2 µs) and TA (92.2 ± 30.2 µs) than HCs (28.3 ± 3.4 µs and 30.9 ± 5.1 µs, respectively). Conclusions: CNE‐SFEMG is sensitive for discovering abnormalities in neuromuscular transmission in LEM. Muscle Nerve 56 : 253–257, 2017 |
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| Keywords: | concentric needle electrode extensor digitorum jitter Lambert‐Eaton myasthenia single fiber electromyography tibialis anterior |
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