| 基于Pentacam HR的角膜屈光指数计算 |
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| 引用本文： | 华焱军,;王勤美,;黄锦海. 基于Pentacam HR的角膜屈光指数计算[J]. 眼科, 2014, 23(5): 308-312. DOI: 10.13281/j.cnki.issn.1004-4469.2014.05.006 |
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| 作者姓名： | 华焱军, 王勤美, 黄锦海 |
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| 作者单位： | 200233.上海交通大学附属第六人民医院眼科（华焱军）；325027 温州医科大学附属眼视光医院屈光手术中心（王勤美、黄锦海） |
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| 摘 要： | 目的 评估Pentacam HR测量角膜屈光术后眼角膜参数的可重复性并比较用Pentacam HR角膜参数计算未手术眼和角膜屈光术后眼角膜屈光指数的差异。设计 前瞻性研究。研究对象 接受角膜屈光手术术前及术后检查者，分为两组：A组为接受常规术前检查者207例207眼；B组为接受常规术前检查且术后3个月（LASIK）或6个月（PRK）以上复查者67例133眼。方法 A组受试眼行主觉验光和Pentacam HR检查；B组受试眼手术前后分别行主觉验光和Pentacam HR检查。两组中Pentacam HR检查均获得三次有效结果。主要指标 变异系数（CVw）、组内标准差（Sw）和组内相关系数（ICC）评估Pentacam HR获得的未手术眼（A组）和角膜屈光术后眼（B组）的角膜中央前表面3 mm范围内平均曲率半径（Ra）、角膜中央后表面3 mm范围内平均曲率半径（Rp）和中央角膜厚度（CCT）的可重复性。独立样本t检验分别分析A组和B组中计算获得的角膜屈光指数的差异。结果 A组中Pentacam HR获得的Ra、Rp和CCT分别为（7.780±0.235）mm、（6.341±0.225）mm和（541.67±31.79）μm； B组中Pentacam HR获得的Ra、Rp和CCT分别为（8.625±0.412）mm、（6.379±0.237）mm和（461.89±34.70）μm，均具有很好的可重复性（CVw均<1%，ICC均≥0.99）。基于Pentacam HR获得的参数计算角膜屈光指数，A组为（1.3278 ± 0.0008）；B组为（1.3227±0.0019）（t=34.634，P=0.000）。结论 Pentacam HR获得的未手术眼和角膜屈光术后眼角膜中央前、后表面3 mm范围内曲率半径和中央角膜厚度均具有很好的可重复性。基于Pentacam HR获得的角膜屈光术后眼的角膜屈光指数小于未手术眼的角膜屈光指数。（眼科， 2014, 23： 308-312）
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| 关 键 词： | 角膜屈光手术 角膜屈光力 角膜屈光指数 PentacamHR |
| 收稿时间： | 2014-02-06 |
Keratometric induce calculated by parameters obtained by Pentacam HR |
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| HUA Yan-jun,WANG Qin-mei,HUANG Jin-hai. Keratometric induce calculated by parameters obtained by Pentacam HR[J]. Ophthalmology in China, 2014, 23(5): 308-312. DOI: 10.13281/j.cnki.issn.1004-4469.2014.05.006 |
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| Authors: | HUA Yan-jun WANG Qin-mei HUANG Jin-hai |
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| Affiliation: | 1. Department of Ophthalmology, Affiliated Sixth People's Hospital Shanghai Jiao Tong University, Shanghai 200233, China; 2. Eye Hospital of Wenzhou Medical University, Wenzhou 325027, China |
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| Abstract: | Objective To assess repeatability of corneal parameters （curvature and central thickness） obtained by Pentacam HR in Chinese normal eyes and eyes after corneal refractive surgery, and to calculate keratometric index based on parameters obtained by Pentacam HR. Design Prospective study. Participants Subjects who received examinations for corneal refractive surgery were divided in to 2 groups. In group A, 207 eyes of 207 myopic subjects who received preoperative examinations were included. In group B, 133 eyes of 67 subjects who received preoperative examinations and postoperative examinations more than 3 month after LASIK or more than 6 month after PRK were included. Method In group A, subjective refraction and Pentacam HR were performed. In group B, subjective refraction and Pentaeam HR were performed preoperatively and postoperatively. Pentacam HR performed 3 times and 3 valid results were obtained for every tested eye in both groups. Main Outcome Measures Coefficient of variation （CVw）, intraclass standard deviation （Sw）, and intraclass correlation coefficient（ICC） were used to evaluate the repeatability of mean anterior central corneal curvature in 3 mm zone（Ra）, mean posterior central corneal curvature in 3 mm zone（Rp） and central corneal thickness（CCT） in both groups. Independent samples t test was used to compare keratometric induce from virgin eyes and post LASIK/PRK eyes. Results In group A, Ra, Rp and CCT obtained by Pentacam HR were （7.780±0.235） mm, （6.341±0.225） mm and （541.67±31.79）μm, respectively; in group B, Ra, Rp and CCT obtained by Pentacam HR were （8.625±0.412） mm, （6.379±0.237） mm and （461.89±34.70） μm, respectively. All the parameters obtained in both groups had good repeatability （all the CVw〈1%, and all the ICC ≥0.99）. The corneal refractive index calculated based on the parameters obtained by Pentacam HR were （1.3278±0.0008） in group A and （1.3227±0.0019） in group B, and the difference was statistically signific |
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| Keywords: | corneal refractive surgery corneal power keratometric index Pentacam HR |
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