登革热疫苗的近期研究进展 |
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引用本文: | 吴师师 吴浩飞 孟胜利. 登革热疫苗的近期研究进展[J]. 国际生物制品学杂志, 2015, 38(4): 181-184. DOI: 10.3760/cma.j.issn.1673-4211.2015.04.007 |
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作者姓名: | 吴师师 吴浩飞 孟胜利 |
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作者单位: | 430207 武汉生物制品研究所有限责任公司科研部(吴师师、吴浩飞),病毒性疫苗研究一室(孟胜利) |
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摘 要: | 登革热已成为世界上分布最广、发病最多的虫媒病毒病。人口增加和流动性增大加剧了登革病毒传播,对人类健康造成了严重威胁。目前尚无针对该病毒的疫苗上市,几种候选疫苗正处于临床试验阶段。此文就登革病毒的结构特征以及一些前景较好的登革热疫苗的研究状况做一综述。
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关 键 词: | 登革热疫苗 登革热病毒 登革出血热 |
Current progress of dengue vaccine development |
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Affiliation: | *Research and Development Department, Wuhan Institute of Biological Products Co., Ltd., Wuhan 430207, China |
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Abstract: | Dengue fever has become the most widely distributed arbovirus disease with the largest incidence over the world. The increase of population and mobility contributes to the spread of dengue virus, threatening human health severely. Currently, no licensed vaccine for dengue virus is available, but several candidates have entered clinical trails. This review summarizes the structural characteristics of dengue virus, and research status of some promising candidate vaccines. |
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Keywords: |   Dengue vaccines Dengue virus Dengue hemorrhagic fever |
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