| 成人种痘样水疱病样淋巴瘤一例并文献复习 |
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| 引用本文： | 杨佼,徐晨琛,崔炳南. 成人种痘样水疱病样淋巴瘤一例并文献复习[J]. 中国麻风皮肤病杂志, 2020, 36(3): 165-167. DOI: 10.12144/zgmfskin202003165 |
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| 作者姓名： | 杨佼 徐晨琛 崔炳南 |
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| 作者单位： | 中国中医科学院广安门医院皮肤科，北京，100053 |
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| 摘 要： | 本文报道1例种痘样水疱病样淋巴瘤并对WHO最新分类、EBV感染相关发病机制、鉴别诊断及治疗方面的相关文献进行复习。患者，男，38岁。全身反复皮疹30年，加重1年，患者病程中伴有发热，皮损预后遗留凹陷性瘢痕。血清EB病毒抗体IgG阳性。皮损组织病理示：真皮全层及皮下脂肪小叶内大量淋巴细胞浸润。免疫组化染色示：CD2(+++)，CD3(++)，CD8(++)，TIA-1(++)，CD56(少量+)，CD20(灶状+) ，Ki-67＞30%。EB病毒原位杂交：阳性。诊断：种痘样水疱病样淋巴瘤。
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| 关 键 词： | 种痘样水疱病样淋巴瘤 种痘样水疱病样淋巴增生性疾病 EB病毒 |
Adult hydroa vacciniforme-like lymphoma:a case report and literature review |
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| YANG Jiao,XU Chenchen,CUI Bingnan. Adult hydroa vacciniforme-like lymphoma:a case report and literature review[J]. China Journal of Leprosy and Skin Diseases, 2020, 36(3): 165-167. DOI: 10.12144/zgmfskin202003165 |
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| Authors: | YANG Jiao XU Chenchen CUI Bingnan |
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| Affiliation: | Department of Dermatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China |
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| Abstract: | A case of hydroa vacciniforme-like lymphoma was reported and the literature of the latest WHO classification,EBV infection-related pathogenesis,differential diagnosis and treatment were reviewed.A 38-year-old male presented with relapsed generalized lesions and fever for 30 years and aggravated for 1 year.Pitted scars were left after lesions relieved.The patient was positive for EB antibodies(IgG).Histopathological examination showed dense infiltration of lymphocytes in the whole dermis and subcutaneous tissue.Immunohistochemistory showed CD2(+++),CD3(++),CD8(++),TIA-1(++),CD56(+),CD20(focal+),Ki-67>30%,EBER(+).The diagnosis of hydroa vacciniforme-like lymphoma was made. |
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| Keywords: | hydroa vacciniforme-like lymphoma hydroa vacciniforme-like lymphoproliferative disorder Epstein-Barr virus |
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