Spontaneous switching of the sucrose-promoted colony phenotype in Streptococcus sanguis. |
| |
| Authors: | G Tardif M C Sulavik G W Jones D B Clewell |
| |
| Affiliation: | Department of Microbiology and Immunology, School of Medicine, University of Michigan, Ann Arbor 48109-0402. |
| |
| Abstract: | Streptococcus sanguis on media containing 3% sucrose gives rise to characteristic hard cohesive colonies (designated Spp+). Populations of Spp+ bacteria (strain Challis) on sucrose media switch to a soft noncohesive phenotype (designated Spp-) at a frequency of 10(-4) to 10(-3). Spp- bacteria switch back to Spp+ bacteria at a similar frequency. Successive rounds of Spp variation were observed. The Spp phenotypic switch was associated with changes in extracellular glucosyltransferase activity. |
| |
| Keywords: | |
|
