| Affiliation: | 1. Department of Intensive Care 4131, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark;2. Centre for Research in Intensive Care (CRIC), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark;3. Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark;4. Department of Public Health, Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark;5. Center for Statistical Science, Peking University, Beijing, China;6. Department of Adult Critical Care, University Hospital of Wales, Cardiff, UK;7. Pharmacy Department, Oxford University Hospitals NHS Foundation Trust, Oxford, UK;8. Department of Intensive Care Medicine, Kuopio University Hospital, Kuopio, Finland;9. Department of Surgical Sciences and Integrated Diagnostics, IRCCS AOU San Martino IST, University of Genoa, Genoa, Italy;10. Department of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;11. Department of Anaesthesia and Intensive Care, Haukeland University Hospital and Clinical Institute 1 UiB, Bergen, Norway;12. Department of Intensive Care Medicine, Inselspital, Bern University Hospital, Bern, Switzerland |
