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三种不同术后镇痛方案应用于腹腔镜全子宫切除术的临床效果观察
引用本文:吴靦,李宇琴,吴演文,蒋红娥,谭美云,刁胜翠,张春元. 三种不同术后镇痛方案应用于腹腔镜全子宫切除术的临床效果观察[J]. 蚌埠医学院学报, 2022, 47(3): 330-333. DOI: 10.13898/j.cnki.issn.1000-2200.2022.03.014
作者姓名:吴靦  李宇琴  吴演文  蒋红娥  谭美云  刁胜翠  张春元
作者单位:1.南方医科大学附属中山市博爱医院 麻醉科,广东 中山 5284032.广东省中山市中医院 内二科,528400
基金项目:计划生育局医学科研项目;广东省中山市卫生
摘    要:目的:比较3种不同术后镇痛方案在腹腔镜全子宫切除术中的应用效果.方法:选择择期行腹腔镜下全子宫切除术病人90例为研究对象,按照随机数字表法分为地佐辛复合曲马多组(DT组)、地佐辛复合氟比洛芬酯组(DF组)、地佐辛复合舒芬太尼组(DS组),各30例.DT、DF、DS组分别采用地佐辛0.5 mg/kg+曲马多10 mg/k...

关 键 词:全子宫切除术  麻醉  术后镇痛  腹腔镜  地佐辛
收稿时间:2019-10-15

Application effects of three different postoperative analgesic regimens in laparoscopic total hysterectomy
WU Mian,LI Yu-qin,WU Yan-wen,JIANG Hong-e,TAN Mei-yun,DIAO Sheng-cui,ZHANG Chun-yuan. Application effects of three different postoperative analgesic regimens in laparoscopic total hysterectomy[J]. Journal of Bengbu Medical College, 2022, 47(3): 330-333. DOI: 10.13898/j.cnki.issn.1000-2200.2022.03.014
Authors:WU Mian  LI Yu-qin  WU Yan-wen  JIANG Hong-e  TAN Mei-yun  DIAO Sheng-cui  ZHANG Chun-yuan
Affiliation:1.Department of Anesthesiology, The Affiliated Boai Hospital of Zhongshan, Southern Medical University, Zhongshan Guangdong 5284032.Internal Medicine 2 Area, Zhongshan Hospital of Traditional Chinese Medicine, Zhongshan Guangdong 528400, China
Abstract:ObjectiveTo compare the clinical effects of three different postoperative analgesic regimens in laparoscopic total hysterectomy.MethodsNinety patients scheduled by laparoscopic total hysterectomy were randomly divided into the dezocine combined with tramadol group(DT group), dezocine combined with flurbiprofen axetil group(DF group) and dezocine combined with sufentanil group(DS group)(30 cases in each group). The DT, DF and DS groups were treated with 0.5 mg/kg dezocine+10 mg/kg tramadol, 0.5 mg/kg dezocine+3 mg/kg flurbiprofen axetil and 0.5 mg/kg dezocine+1 μg/kg sufentanil for postoperative patient controlled intravenous analgesia(PCIA), respectively. The VAS score ≤3 points was maintained.If VAS score > 3 points, the 0.1 mg/kg dizocine was added in a single dose. The Ramsay sedation score and BCS comfort score among three groups were recorded after 2 h, 4 h, 8 h, 12 h and 24 h of surgery. The dose of dezocine, dose of additional dezocine, number of PCIA, postoperative bowel sounds recovery time, first anal exhaust time, first time out of bed activity, nausea, vomiting, bloating and dizziness among three groups were recorded.ResultsCompared with the DT group and DS group, the postoperative bowel sound recovery time, first anal exhaust time and first time of getting out of bed activity were significantly shortened(P < 0.05), and the postoperative nausea, abdominal distension and dizziness significantly reduced in the DF group(P < 0.05). There was no statistical significance in Ramsay sedation score and BCS comfort score among three groups after 2 h, 4 h, 8 h, 12 h and 24 h of surgery, and the differences of the dose of dezocine, dose of additional dezocine and number of PCIA were not statistically significant(P > 0.05).ConclusionsDezoxin combined with flurbiprofen axetil is more beneficial to the recovery of gastrointestinal function on the basis of satisfying postoperative analgesia.
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