Comparison of Four Serological Tests To Determine the CagA or VacA Status of Helicobacter pylori Strains |
| |
| Authors: | Yoshio Yamaoka Tadashi Kodama David Y. Graham Kei Kashima |
| |
| Affiliation: | Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030,1. and Third Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kamikyo-ku, Kyoto, 602 Japan2. |
| |
| Abstract: | We compared four tests for antibodies to CagA or VacA, HelicoBlot 2.0, RIDA Blot Helicobacter, CHIRON RIBA H. pylori SIA, and an enzyme-linked immunosorbent assay using recombinant CagA. Immunoblot assays were accurate for determining Helicobacter pylori status but poor for determining CagA or VacA status (accuracy, 66 to 80% for CagA status and 34 to 67% for VacA status). None can be recommended for determining CagA or VacA status. |
| |
| Keywords: | |
|
|
