| CRT术后极短期心功能改变与中长期反应性的相关性 |
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| 引用本文： | 郭兰燕,张敏霞,胡淼阳,杨华,刘兵,沈敏,程何祥. CRT术后极短期心功能改变与中长期反应性的相关性[J]. 心脏杂志, 2019, 31(2): 144-147. DOI: 10.12125/j.chj.201808021 |
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| 作者姓名： | 郭兰燕 张敏霞 胡淼阳 杨华 刘兵 沈敏 程何祥 |
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| 作者单位： | 空军军医大学第一附属医院心脏内科，陕西 西安 710032 |
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| 基金项目： | 陕西省社会发展科技攻关项目资助（2016SF-289） |
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| 摘 要： | 目的通过复查心脏再同步化治疗(cardiac resynchronization therapy,CRT)术后极短期内的心脏超声,评估双心室同步起搏的效果以及与CRT术后中长期反应的相关性。方法收集行CRT-P/D,术后平均5 d内(简称术后)复查了心脏彩超、心电图、脑钠尿肽前体(pro-BNP)等相关检查,且完成起搏器门诊首次随访(随访1,平均术后2个月)和二次随访(随访2,平均术后6个月),包括心脏彩超、心电图等辅助检查的18例患者。结果 18例入选患者平均随访6个月时,4例(22%)为超反应,7例(39%)为无反应,11例(61%)为有反应(包括超反应)。CRT有反应和无反应组在性别、年龄、扩心病、心脏大小和心功能等方面均无统计学差异CRT有反应组术后左室射血分数(LVEF)与术前、随访1和随访2的LVEF均有显著差异(P<0.05或P<0.01);而无反应组以上均无统计学差异。相关分析提示术后LVEF与随访1和随访2的LVEF值显著正相关,与体质量指数(BMI)呈负相关(均P<0.05)。结论术后极短期心功能LVEF值的变化与CRT术后中长期的反应性可能相关。
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| 关 键 词： | 心脏再同步化治疗 左室射血分数 心力衰竭 |
| 收稿时间： | 2018-08-14 |
Correlation of LVEF after CRT treatment for 5 days and the mid-long term responsiveness |
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| GUO Lan-yan,ZHANG Min-xia,HU Miao-yang,YANG Hua,LIU Bing,SHEN Min,CHENG He-xiang. Correlation of LVEF after CRT treatment for 5 days and the mid-long term responsiveness[J]. Chinese Heart Journal, 2019, 31(2): 144-147. DOI: 10.12125/j.chj.201808021 |
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| Authors: | GUO Lan-yan ZHANG Min-xia HU Miao-yang YANG Hua LIU Bing SHEN Min CHENG He-xiang |
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| Affiliation: | Department of Cardiology, First Affiliated Hospital, Air Force Medical University, Xi’an 710032, Shaanxi, China |
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| Abstract: | AIM Echocardiography results, after CRT implantation for 5 days, to estimate the effects of biventricular pacing and correlations with the mid-long term responsiveness of CRT. METHODS We collect 18 patients received CRT-P/D implantation who all conducted echocardiography (Echo)、12-leads surface electracardiogram (ECG)、Pro-BNP and so on before implantation and 5 days after procedure（post-implantation）, also completed the first visit (visit1, 2 months after CRT) and the second visit (visit2, 6 months after CRT) in clinic. RESULTS Among all the collected patients, 11 were the responders, including 4 super-responders, and the left 7 were the non-responders. There existed no evident difference in sex、age、DCM、heart size and heart function between the two groups. There existed evident difference between post-EF and pre-EF/visit1 EF/visit2 EF in the responders group (all P<0.05), otherwise, no difference was observed between the above parameters in non-responders group. Correlation analysis showed that LVEF of post-implantation was positively correlated to LVEF of visit 1 and visit 2, and negatively to BMI (all P<0.05). CONCLUSION The change of post-LVEF correlated with the mid-long term CRT response in some extent. |
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| Keywords: | cardiac resynchronization left ventricular ejection fraction heart failure |
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