| 中心性浆液性脉络膜视网膜病变的谱域光学相干断层扫描特征 |
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| 引用本文： | 杜虹,戴荣平,董方田. 中心性浆液性脉络膜视网膜病变的谱域光学相干断层扫描特征[J]. 协和医学杂志, 2013, 4(2): 160-164. DOI: 10.3969/j.issn.1674-9081.2013.02.016 |
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| 作者姓名： | 杜虹 戴荣平 董方田 |
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| 作者单位： | 中国医学科学院 北京协和医学院 北京协和医院眼科, 北京 100730 |
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| 摘 要： | 目的 观察中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy, CSC)的谱域光学相干断层扫描(spectral domain optical coherence tomography, SD-OCT)图像特征。 方法 对临床上已确诊为CSC的34例(40只眼)患者进行SD-OCT和荧光素眼底血管造影(fundus fluorescein angiography, FFA)检查, 分析其图像特征并对二者结果进行比较。 结果 40只眼的SD-OCT检查结果显示, 37只眼(92.5%)有黄斑区局限性神经上皮脱离, 3只眼(7.5%)仅有色素上皮脱离。神经上皮脱离的37只眼中, 9只眼(24.3%)感光细胞内外节结合部信号增强、增厚, 28只眼(75.7%)信号减弱或消失; 伴有色素上皮脱离20只眼(54.1%), 伴有色素上皮层增厚、不规则或隆起12只眼(32.4%), 仅有神经上皮脱离5只眼(13.5%)。3只眼SD-OCT与FFA均表现为色素上皮脱离者, 二者色素上皮脱离位置和大小相一致。28只眼FFA表现为荧光渗漏点者, SD-OCT在相应位置均有色素上皮增厚、不规则、隆起或脱离。SD-OCT较FFA能发现更多的色素上皮脱离和神经上皮脱离。 结论 CSC患者的SD-OCT多数在神经上皮脱离区内存在视网膜色素上皮的增厚、不规则、隆起或脱离, 感光细胞内外节结合部信号多数减弱或消失。
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| 关 键 词： | 中心性浆液性脉络膜视网膜病变 谱域光学相干断层扫描 荧光素眼底血管造影 视网膜色素上皮 |
| 收稿时间： | 2013-02-06 |
Spectral Domain Optical Coherence Tomography in Patients with Central Serous Chorioretinopathy |
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| DU Hong,DAI Rong-ping,DONG Fang-tian. Spectral Domain Optical Coherence Tomography in Patients with Central Serous Chorioretinopathy[J]. Medical Journal of Peking Union Medical College Hospit, 2013, 4(2): 160-164. DOI: 10.3969/j.issn.1674-9081.2013.02.016 |
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| Authors: | DU Hong DAI Rong-ping DONG Fang-tian |
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| Affiliation: | Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China |
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| Abstract: | Objective To study the clinical features of spectral domain optical coherence tomography （SD-OCT） scanning in patients with central serous chorioretinopathy （CSC）. Methods Thirty-four patients （40 eyes） with confirmed CSC underwent SD-OCT scanning and fundus fluorescein angiography （FFA）. Clinical findings in both examinations were analyzed and compared. Results As shown by SD-OCT, local neuro-retina detachments in macular areas were found in 37 of 40 eyes （92. 5% ）, and retinal pigment epithelium （RPE） de- tachments without neuro-retina detachments were found in 3 eyes （7.5%）. In the eyes with neoro-retina detach- ments, high and thickened signals of photoreceptor inner segment/outer segment （IS/OS） junction were found in 9 eyes （24. 3% ）, and low or disappeared signals of IS/OS junction were found in 28 eyes （75.7%）. Twenty of 37 eyes （54. 1% ） with neuro-retina detachments had RPE detachments, 12 eyes （32. 4% ） had small RPE elevations or thickened RPE layer. RPE detachments in both SD-OCT and FFA in 3 eyes kept consistent. In 28 eyes, RPE lesions in SD-OCT were found in the same area of the fluorescein leakage spots in FFA. More RPE detachments and neuro-retina detachments were found in SD-OCT than in FFA. Conclusions Small RPE elevations, thickened RPE layer, or RPE detachments can be found in the retinal detachment areas by SD-OCT in most CSC patients. Low or disappeared signals may exist in the IS/OS junction. |
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| Keywords: | central serous chorioretinopathy spectral domain optical coherence tomography fundus fluorescein angiography retinal pigment epithelium |
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