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实时剪切波弹性成像在甲状腺K-TIRADS 3-5类结节诊断中的应用价值
引用本文:杭 菁,叶新华,袁 涛. 实时剪切波弹性成像在甲状腺K-TIRADS 3-5类结节诊断中的应用价值[J]. 现代肿瘤医学, 2019, 0(15): 2745-2748. DOI: 10.3969/j.issn.1672-4992.2019.15.029
作者姓名:杭 菁  叶新华  袁 涛
作者单位:南京医科大学第一附属医院超声科,江苏 南京 210029
摘    要:目的:探讨实时剪切波弹性成像(shear wave elastography,SWE)在K-TIRADS 3-5类甲状腺结节诊断中的应用价值。方法:回顾性分析K-TIRADS 3-5类之间的甲状腺手术患者,探讨实时SWE技术在其中的诊断价值,筛选出效能最佳的定量弹性指标,得出诊断界值。结果:入组244例患者289个结节,其中恶性结节170个,良性结节119个。结节病灶区的杨氏模量最大值Emax是用于鉴别结节性质效能最佳的指标,AUC为0.764,P<0.001,且Emax=52.7 kPa时鉴别K-TIRADS 3-5类结节良恶性的敏感度、特异度分别为75.3%、73.1%。结论:实时SWE技术可用于K-TIRADS 3-5类甲状腺结节的鉴别,Emax是诊断效能最佳的定量弹性指标。

关 键 词:甲状腺结节  实时剪切波超声弹性成像  杨氏模量最大值  K-TIRADS

Application values of shear wave elastography in K-TIRADS 3-5 category thyroid nodules
Hang Jing,Ye Xinhua,Yuan Tao. Application values of shear wave elastography in K-TIRADS 3-5 category thyroid nodules[J]. Journal of Modern Oncology, 2019, 0(15): 2745-2748. DOI: 10.3969/j.issn.1672-4992.2019.15.029
Authors:Hang Jing  Ye Xinhua  Yuan Tao
Affiliation:Department of Ultrasound,the First Affiliated Hospital of Nanjing Medical University,Jiangsu Nanjing 210029,China.
Abstract:Objective:To evaluate the utility of shear wave elastography(SWE) in diagnosing K-TIRADS 3-5 category thyroid nodules.Methods:A group of 289 thyroid nodules with K-RADS 3-5 category were enrolled in our research.We performed grey-scale ultrasound and 2D-SWE examinations before operation.All the nodules were divided into two groups according to the pathological result.We used statistical software to investigate different parameters between two groups.Results:Totally 170 malignant and 119 benign nodules were performed in our study.SWE measurements were significantly different between two categories.The maximum Young's modulus value was considered to be the best parameter in disgnosing thyrois nodules.On ROC curve,the area under the curve (AUC) of the maximum Young's modulus value was 0.764.Taking 52.7 kPa as the threshold of maximum Young's modulus value,the sensitivity was 75.3% and specificity was 73.1%.Conclusion:The maximum Young's modulus value can help diagnose malignant thyroid nodules with K-TIRADS 3-5 category.
Keywords:thyroid nodules   shear wave elastography   maximum young's modulus   K-TIRADS
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