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In vitro activity of a new echinocandin, LY303366, compared with those of amphotericin B and fluconazole against clinical yeast isolates.
Authors:O Uzun, S Kocag  z, Y Cetinkaya, S Arikan,   S Unal
Affiliation:O Uzun, S Kocagöz, Y Cetinkaya, S Arikan, and S Unal
Abstract:The in vitro activity of LY303366, a new echinocandin derivative, was evaluated with 191 yeast isolates by a broth microdilution method. The MICs at which 50% of the isolates were inhibited were 0.125 microg/ml for Candida albicans and C. tropicalis, 0.25 microg/ml for C. krusei, C. kefyr, and C. glabrata, and 2.0 microg/ml for C. parapsilosis.
Keywords:
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