| 超声心动图评价犬急性心肌梗死早期左心室重构的实验研究 |
| |
| 引用本文： | 王健,康春松,郑艳萍,薛继平,张蕊. 超声心动图评价犬急性心肌梗死早期左心室重构的实验研究[J]. 中华医学超声杂志(电子版), 2008, 5(2): 10-12 |
| |
| 作者姓名： | 王健 康春松 郑艳萍 薛继平 张蕊 |
| |
| 作者单位： | 1. 山西医科大学第一医院超声科,太原,030001
2. 山西晋中榆次武警8650部队医院 |
| |
| 摘 要： | 目的 采用超声心动图检测犬急性心肌梗死(AMI)后左心室重构发生时间及6 h内左心室重构变化.方法 对14只健康成年犬麻醉后开胸结扎左冠状动脉左前降支制备AMI模型,成功制备8只AMI模型,超声心动图分别于术前,术后1、2、3、4、5及6 h观察梗死心肌室壁厚度(WIT)、室壁运动积分指数(WMSI)、左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)、左心室射血分数(LVEF).检查结束后处死实验犬,取梗死区心肌组织行病理学检查.结果 与术前比较,术后1 h实验犬WMSI、LVESV(P<0.01)和LVEDV(P<0.05)增大,LVEF和WIT减小(P<0.01);WMSI术后3、4、5、6 h高于术后1 h(P<0.05);术后4、5、6 h和术后2 h比较,LVEDV和LVESV增高,LVEF降低.病理检查显示:梗死区心肌细胞发生肿胀,肌浆呈颗粒状凝集而分布不均,出现核固缩.结论 犬AMI后1 h即可出现左心室重构,超声心动图可评估AMI后早期左心室重构.
|
| 关 键 词： | 超声心动描记术 心肌梗死 心室复建 |
Echocaridiographic evaluation on early left ventricular remodeling after acute myocardial infarction:experimental study |
| |
| WANG Jian,KANG Chun-song,ZHENG Yan-ping,XUE Ji-ping,ZHANG Rui. Echocaridiographic evaluation on early left ventricular remodeling after acute myocardial infarction:experimental study[J]. Chinese Journal of Medical Ultrasound, 2008, 5(2): 10-12 |
| |
| Authors: | WANG Jian KANG Chun-song ZHENG Yan-ping XUE Ji-ping ZHANG Rui |
| |
| Affiliation: | WANG Jian,KANG Chun-song,ZHENG Yan-ping,XUE Ji-ping,ZHANG Rui.Department of Ultrasonography,The First Hospital of Shanxi Medical University,Taiyuan 030001,China |
| |
| Abstract: | Objective To investigate the onset of left ventricular remodeling(LVRM)after acute myocardium infarction(AMI)and its changes within 6 hours in dogs on echocardiography.Methods AMI was induced in 14 dogs by ligating the left anterior descending arteries.Eight myocardium infarcted models were successful and were sacrified for pathological study.The indices of LVRM:wall infarction thickness(WIT),the wall motion score index(WMSI),left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(... |
| |
| Keywords: | Echocardiography Myocardial infarction Ventricular remodeling |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中华医学超声杂志(电子版)》浏览原始摘要信息 |
|
点击此处可从《中华医学超声杂志(电子版)》下载全文 |
|
