| 125I粒子条植入治疗原发性肝癌伴门静脉主干癌栓的近期疗效 |
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| 引用本文： | 武京鹏,何东风. 125I粒子条植入治疗原发性肝癌伴门静脉主干癌栓的近期疗效[J]. 中华介入放射学电子杂志, 2015, 3(3): 144-147. DOI: 10.3877/cma.j.issn.2095-5782.2015.03.008 |
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| 作者姓名： | 武京鹏 何东风 |
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| 作者单位： | 1. 150081 哈尔滨医科大学附属肿瘤医院介入科 |
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| 基金项目： | 黑龙江省科技厅青年自然科技基金(QC08C06) |
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| 摘 要： | 目的探讨125I粒子条植入治疗原发性肝癌伴门静脉主干癌栓的安全性及近期疗效。 方法15例原发性肝癌伴门静脉主干癌栓患者行门静脉125I粒子条植入术，手术操作在超声及DSA引导下进行。术后对肝功能、血常规及凝血功能的变化、癌栓的改变、不良反应进行评价。 结果所有患者均成功植入放射性125I粒子条，门静脉主干癌栓的有效率为40.00%(6/15)，疾病控制率为86.67%(13/15)。术后2个月复查所有患者的肝功能、血常规、凝血功能与术前比较差异无统计学意义。未出现与粒子条植入相关的严重并发症。 结论植入125I粒子条治疗肝癌伴门静脉主干癌栓是安全、可行、有效的。
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| 关 键 词： | 肝肿瘤 门静脉主干癌栓 125I粒子条 |
| 收稿时间： | 2014-07-04 |
Evaluation the efficacy of 125I seed strand implantation for treatment of hepatocellular carcinoma with main portal vein tumor thrombus |
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| Jingpeng Wu,Dongfeng He. Evaluation the efficacy of 125I seed strand implantation for treatment of hepatocellular carcinoma with main portal vein tumor thrombus[J]. Chinese Journal of Interventional Radiology (Electronic Edition), 2015, 3(3): 144-147. DOI: 10.3877/cma.j.issn.2095-5782.2015.03.008 |
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| Authors: | Jingpeng Wu Dongfeng He |
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| Affiliation: | 1. Department of Interventional Therapy, The Affiliated Tumor Hospital of Harbin Medical University, Harbin 150081, China |
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| Abstract: | ObjectiveTo discuss the therapeutic efficacy and safety of 125I seed strand implantation for treatment of hepatocellular carcinoma (HCC) with main portal vein tumor thrombus (MPVTT). MethodsA total of 15 patients with confirmed HCC accompanied by MPVTT received implantation of 125I seed strand via portal vein. The procedure was guided by ultrasound and DSA. The hepatic function, routine blood test as well as coagulation function, the changes of PVTT and the postoperative complications were analyzed. ResultsThe implantation of 125I seed strand was successfully accomplished in all the patients. The objective response rate of MPVTT was 40.00% (6/15) and the disease control rate was 86.67% (13/15). There was no significant difference between preoperative and postoperative two months in hepatic function, routine blood test and coagulation function. No serious procedure-related complications occurred. ConclusionsImplantation of 125I seed strand is safe, feasible and effective to treat MPVTT in HCC. |
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| Keywords: | Liver neoplasms Main portal vein tumor thrombus 125I seed strand |
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