| 高胆红素血症新生儿215例抗体检测情况分析 |
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| 引用本文： | 刘磊,张杏杏,夏帮坤,姚倩,李玉云. 高胆红素血症新生儿215例抗体检测情况分析[J]. 蚌埠医学院学报, 2021, 46(8): 1096-1098. DOI: 10.13898/j.cnki.issn.1000-2200.2021.08.028 |
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| 作者姓名： | 刘磊 张杏杏 夏帮坤 姚倩 李玉云 |
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| 作者单位： | 1.安徽省阜阳市人民医院 输血科, 2360012.蚌埠医学院 检验医学院, 安徽 蚌埠 233030 |
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| 基金项目： | 蚌埠医学院研究生创新课题基金Byycxz1608 |
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| 摘 要： | 目的:对高胆红素血症(NHB)新生儿溶血三项试验抗体检测情况进行分析,探究早期检测的临床意义.方法:对出生3 d内被确诊为NHB的新生儿215例采集静脉血进行血型检测、直抗试验、游离试验和释放试验,并对检测结果进行分析.结果:215例NHB患儿中,共有97例确诊为新生儿溶血病(HDN),其中HDN组A、B、O型占比分别...
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| 关 键 词： | 高胆红素血症 新生儿溶血病 新生儿 溶血三项试验 |
| 收稿时间： | 2020-08-21 |
Analysis of the antibody detection in 215 neonates with hyperbilirubinemia |
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| LIU Lei,ZHANG Xing-xing,XIA Bang-kun,YAO Qian,LI Yu-yun. Analysis of the antibody detection in 215 neonates with hyperbilirubinemia[J]. Journal of Bengbu Medical College, 2021, 46(8): 1096-1098. DOI: 10.13898/j.cnki.issn.1000-2200.2021.08.028 |
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| Authors: | LIU Lei ZHANG Xing-xing XIA Bang-kun YAO Qian LI Yu-yun |
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| Affiliation: | 1.Department of Blood Transfusion, Fuyang People's Hospital, Fuyang Anhui 2360012.School of Laboratory Medicine, Bengbu Medical College, Bengbu Anhui 233030, China |
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| Abstract: | ObjectiveTo analyze the antibody detection results of three hemolysis tests in 215 neonates with hyperbilirubinemia(NHB), and explore the clinical significance of early detection.MethodsThe venous blood in 215 neonates diagnosed with NHB within 3 days after birth were collected, the blood group test, direct resistance test, free test and release test were performed, and the results were analyzed.ResultsAmong 215 children with NHB, 97 cases were diagnosed with hemolytic disease of the newborn(HDN).The percentages of type A, type B and type O in the HDN group were 52.58%(51/97), 45.36%(44/97) and 2.20%(2/97), respectively, and the differences of composition ratio of type A, type B and type O between HDN group and non-HDN group were statistically significant(χ2=61.49, P < 0.01).The positive rates of the release test, free test and direct resistance test were 100%(97/97), 78.35%(76/97) and 16.50%(16/97), respectively.The differences of the detection rates among three methods were statistically significant(χ2=160.04, P < 0.01), and which in release test, free test and direct resistance test gradually decreased in turn.ConclusionsThrough rapid detection of HDN microcolumn gel card, the timely diagnosis can be made, so as to select appropriate methods for positive symptomatic treatment. |
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