| 美托洛尔缓释片对阵发性心房颤动射频消融术后早期复发的影响 |
| |
| 引用本文： | 孙飞,魏子秀. 美托洛尔缓释片对阵发性心房颤动射频消融术后早期复发的影响[J]. 心脏杂志, 2020, 32(1): 46-49. DOI: 10.12125/j.chj.201910031 |
| |
| 作者姓名： | 孙飞 魏子秀 |
| |
| 作者单位： | 1.济宁医学院临床医学院2017级研究生,山东 济宁 272000 |
| |
| 摘 要： | 目的 探究美托洛尔缓释片对阵发性心房颤动(PAF)射频消融术后早期复发的影响。 方法 收集2017年10月至2019年5月于济宁市第一人民医院心内科收治的PAF患者100例,采用随机数字表法分为试药组（n = 48）和对照组(n = 52)。两组均行射频消融术治疗,术后对照组采用常规胺碘酮治疗,试药组联合美托洛尔缓释片治疗,比较两组患者血清炎性因子、心功能指标、不良反应及预后。两组疗程均为3个月。 结果 试药组早期复发率4%,对照组早期复发率为14%,两组比较差异有统计学意义（P < 0.05）;射频消融术后1个月及术后3个月两组C反应蛋白（CRP）、白介素（IL）-6、肿瘤坏死因子（TNF）-α、左房前后径（LAD）值呈下降趋势,左室射血分数（LVEF）值呈上升趋势,且试药组与对照组相比差异有显著统计学意义（P < 0.05, P < 0.01）;术前、术后1个月和术后3个月随访时采用简明健康调查表（SF-36）评估生活质量,对照组及试药组组内术后3个月躯体健康评分（PCS）和精神健康评分（MCS）显著改善,但组间的改善没有统计学差异。 结论 美托洛尔缓释片联合胺碘酮可降低阵发性房颤射频消融术后早期的复发率,效果优于单用胺碘酮。
|
| 关 键 词： | 心房颤动,阵发性 美托洛尔 射频消融术 早期复发 |
| 收稿时间： | 2019-10-21 |
Effect of metoprolol sustained-release tablets on early recurrence after radiofrequency ablation of paroxysmal atrial fibrillation |
| |
| Affiliation: | 1.2017 Graduate Student of Clinical Medicine, Jining Medical University, Jining 272000, Shandong, China2.Department of Cardiology, Jining NO.1 People's Hospital, Jining 272000, Shandong, China |
| |
| Abstract: | AIM To investigate the effect of metoprolol on early recurrence after radiofrequency ablation of paroxysmal atrial fibrillation. METHODS A total of 100 patients with paroxysmal atrial fibrillation admitted to the Department of Cardiology, First People's Hospital of Jining City from October 2017 to May 2019 were enrolled. The patients were divided into observation group and control group by random number table, 48 patients in the observation group and 52 patients in the control group. Radiofrequency ablation was performed in both groups. The control group was treated with conventional amiodarone. The observation group was combined with metoprolol sustained-release tablets. The serum inflammatory factors, cardiac function indexes, adverse reactions and prognosis of the two groups were compared. Both groups were treated for 3 months. RESULTS The early recurrence rate of the observation group was 4, and the early recurrence rate of the control group was 14%. The difference between the two groups was statistically significant (P < 0.05).CRP、IL-6、TNF-α levels and LAD values in two groups after 1 month and 3 months after radiofrequency ablation showed a downward trend, and the LVEF value showed an upward trend. The difference between the observation group and the control group was statistically significant (P < 0.05, P < 0.01). The preoperative,1 month after operation and 3 month after operation follow-up. The quality of life was assessed by SF-36. The physical health score (PCS) and mental health score (MCS) were significantly improved in the control group and the observation group within 3 months after surgery, but there was no significant difference between two groups. CONCLUSION Metoprolol sustained-release tablets combined with amiodarone reduces the early recurrence rate after radiofrequency ablation of paroxysmal atrial fibrillation, and the effect is better than that of amiodarone alone. |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《心脏杂志》浏览原始摘要信息 |
|
点击此处可从《心脏杂志》下载免费的PDF全文 |
|
