Modulation of transport and metabolism of bile acids and bilirubin by chlorogenic acid against hepatotoxicity and cholestasis in bile duct ligation rats: involvement of SIRT1‐mediated deacetylation of FXR and PGC‐1α期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Modulation of transport and metabolism of bile acids and bilirubin by chlorogenic acid against hepatotoxicity and cholestasis in bile duct ligation rats: involvement of SIRT1‐mediated deacetylation of FXR and PGC‐1α

Authors:	Lili Zhu Lei Wang Fei Cao Peng Liu Haidong Bao Yumei Yan Xin Dong Dong Wang Zhongyu Wang Peng Gong

Affiliation:	1. Department of Gynaecology and Obstetrics, The First Affiliated Hospital of Dalian Medical University, Dalian, China;2. Department of Anesthesiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China;3. Department of Hepatobiliary Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, China;4. Department of Gastrointestinal Endoscopy, The First Affiliated Hospital of Dalian Medical University, Dalian, China;5. Department of Ultrasound, The First Affiliated Hospital of Dalian Medical University, Dalian, China;6. Department of Hepatobiliary Surgery, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China

Abstract:

Keywords:	Chlorogenic acid Cholestasis Farnesoid X receptor Hepatotoxicity Peroxisome proliferator‐activated receptor γ coactivator 1‐α Sirtuin 1