Successful Topical Rapamycin Treatment for Facial Angiofibromata in Two Children |
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| Authors: | Emma V. Pynn M.B.Ch.B. M.R.C.P. Jemma Collins M.B.B.Ch. M.R.C.P. Prasad R. Y. Hunasehally M.B.B.S. M.R.C.P. Jenny Hughes M.B.Ch.B. F.R.C.P. |
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| Affiliation: | 1. Welsh Institute of Dermatology, University Hospital of Wales, Cardiff, Wales, UK;2. Dermatology Department, Princess of Wales Hospital, Bridgend, Wales, UK |
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| Abstract: | Topical sirolimus, or rapamycin, is known to inhibit tumorigenesis in tuberous sclerosis. We report two cases of successful treatment of children with facial angiofibromata and summarize the encouraging evidence of the effectiveness of this therapy in the literature. |
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