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Prediction of long‐term prognosis by heteroplasmy levels of the m.3243A>G mutation in patients with the mitochondrial encephalomyopathy,lactic acidosis and stroke‐like episodes syndrome
Authors:W. Bougouin  C. Jardel  A. Lombès  H. M. Bécane  N. Berber  T. Stojkovic  A. Béhin  B. Eymard  D. Duboc  K. Wahbi
Affiliation:1. INSERM Unit 970, Paris Cardiovascular Research Centre (PARCC), Paris, France;2. Paris‐Descartes, Sorbonne Paris Cité University, Paris, France;3. Medical Intensive Care Unit, AP‐HP, Cochin Hospital, Paris, France;4. Biochemistry Department, AP‐HP, Pitié‐Salpêtrière Hospital, Paris, France;5. INSERM U1016, CNRS UMR 8104, Institut Cochin, Paris, France;6. AP‐HP, Pitié‐Salpêtrière Hospital, Reference Centre for Muscle Diseases Paris‐Est, Myology Institute, Paris, France;7. Myology Institute, Pitié‐Salpêtrière Hospital, Pierre et Marie Curie Paris 6 University, Paris, France;8. Department of Cardiology, AP‐HP, Cochin Hospital, Paris Descartes University, Paris, France
Abstract:
Keywords:death  lactic acidosis and stroke‐like episodes  mitochondrial diseases  mitochondrial encephalomyopathy  mutation load  prognosis
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