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美沙酮维持治疗依从性影响因素的多元logistic回归分析
引用本文:赵丽娜,王大勇,张洪淼,叶振淼,金茜,苏德华,邓为民,陈丽秀,陈钢. 美沙酮维持治疗依从性影响因素的多元logistic回归分析[J]. 疾病监测, 2012, 27(5): 388-391. DOI: 10.3784/j.issn.1003-9961.2012.5.017
作者姓名:赵丽娜  王大勇  张洪淼  叶振淼  金茜  苏德华  邓为民  陈丽秀  陈钢
作者单位:温州市疾病预防控制中心;乐清县疾病预防控制中心;温州市戒毒中心;浙江省疾病预防控制中心
摘    要:目的 探讨美沙酮维持治疗(MMT)依从性的相关影响因素,为提高美沙酮维持治疗的依从性、发挥其综合作用提供指导依据。 方法 于2010年12月20-31日对方便抽样抽取的温州市乐清县、永嘉县、苍南县3所美沙酮维持治疗门诊的维持组及脱失组共962人进行问卷调查,运用多元非条件logistic 回归分析找出影响治疗依从性的相关因素。 结果 使用美沙酮后出现不良反应、最初参加MMT时决心弱、门诊医生服务态度一般、未在门诊接受过艾滋病宣教、参加MMT没能提高生活质量是MMT脱失发生的危险因素,OR值分别为46.53、2.91、3.35、2.08 和2.53(P0.05);治疗期间不清楚如何获得毒品为脱失的保护因素。此外,维持组和脱失组在婚姻状况、月收入、家人对治疗的态度、与非吸毒朋友的交往、治疗剂量、消极感受、门诊位置及开诊时间是否方便上差异有统计学意义(P0.05)。 结论 加强门诊医务人员的治疗技能和心理干预技巧,强化服务意识,改善服务态度,建立社会支持,开展多元化及人性化的服务模式已成为提高美沙酮维持治疗依从性、发挥其综合作用的重要手段。

关 键 词:美沙酮维持治疗   依从性   影响因素   多元logistic 回归分析
收稿时间:2012-02-14

Multivariate logistic regression analysis on influencing factors on compliancy to methadone maintenance treatment
ZHAO Li-na,WANG Da-yong,ZHANG Hong-miao,YE Zhen-miao,JIN Qian,SU De-hua,DENG Wei-min,CHEN Li-xiu,CHEN Gang. Multivariate logistic regression analysis on influencing factors on compliancy to methadone maintenance treatment[J]. Disease Surveillance, 2012, 27(5): 388-391. DOI: 10.3784/j.issn.1003-9961.2012.5.017
Authors:ZHAO Li-na  WANG Da-yong  ZHANG Hong-miao  YE Zhen-miao  JIN Qian  SU De-hua  DENG Wei-min  CHEN Li-xiu  CHEN Gang
Affiliation:. Wenzhou Center for Disease Control and Prevention,Wenzhou 325027,Zhejiang,China
Abstract:Objective To explore related influencing factors on drug users’ compliancy to methadone maintenance treatment(MMT) and provide evidence to improve their compliancy to MMT.Methods In December 2010,the questionnaire survey was conducted among 962 drug users receiving MMT in Yueqing,Yongjia and Cangnan counties in Wenzhou and multivariate logistic regression analysis was conducted to understand the influencing factors on their compliancy to MMT.Results The analysis indicated that the adverse reaction of treatment,weak willing of participants,unsatisfied attitude of medical workers,receiving no education about AIDS and unimproved life quality after reviving MMT were the negative factors on the MMT compliancy with the OR value of 46.53,2.91,3.35,2.08 and 2.53 respectively(P<0.05),drug unavailability during the treatment was the positive factor.In addition,the differences on the marital status,economic income,family member’s attitude to MMT,contact with people who didn’t use drug,treatment dosage,negative emotion,MMT clinic’s location and service time of the clinics between the drug users who continued treatment or stopped treatment had statistical significance(P<0.05).Conclusion It is essential to improve the MMT clinic service in both intervention skill and service attitude to increase drug users’ compliancy to MMT for the purpose of AIDS prevention and control.
Keywords:methadone maintenance treatment  compliancy  influencing factor  multivariate logistic regression analysis
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