首页 | 本学科首页   官方微博 | 高级检索  
     

精神分裂症中医证候要素诊断量表初步研究
引用本文:精神分裂症中医证候要素诊断量表初步研究. 精神分裂症中医证候要素诊断量表初步研究[J]. 首都医科大学学报, 2018, 39(6): 821-827. DOI: 10.3969/j.issn.1006-7795.2018.06.006
作者姓名:精神分裂症中医证候要素诊断量表初步研究
作者单位:1. 首都医科大学附属北京安定医院 北京市中西医结合精神卫生研究所 北京脑重大疾病研究院精神分裂症研究所 精神疾病诊断与治疗北京市重点实验室, 北京 100088;2. 厦门市仙岳医院, 福建厦门 361012;3. 唐山市精神卫生中心 唐山市第五医院, 河北唐山 063000;4. 无锡市精神卫生中心, 江苏无锡 214063;5. 洛阳市第五人民医院, 河南洛阳 471000;6. 西安市精神卫生中心, 西安 710061;7. 沈阳市精神卫生中心, 沈阳 110168
摘    要:目的 建立精神分裂症中医证候要素诊断量表,促进精神分裂症中医证候标准化研究。方法 制定精神分裂症中医证候要素调查表,收集302例精神分裂症患者的四诊信息,对中医四诊信息进行频数分析,保留出现频率>10%的四诊信息条目,利用因子分析提取中医证候要素和四诊信息条目,运用二项Logistic回归方法进行进一步的条目筛选和确定条目权重系数,不同四诊信息权重系数不同,对302例患者进行重新打分,以专家辨证所得的证候要素为状态变量(Y),以重新打分所获得的证候要素分值作为检测变量(X)进行受试者工作特征(receiver operating characteristic, ROC)曲线分析,确定各证候要素的诊断阈值。结果 精神分裂症中医证候要素诊断量表包含病位类证候要素6项,分别为:火热、气虚、气滞/气郁、阴虚、血瘀和阳虚,病位类的证候要素4项,分别为:心、肝、脾、胆,每一证候要素诊断量表的总分为100分,诊断域值为60分。结论 精神分裂症中医证候要素诊断量表的研制将促进精神分裂症中医证候标准化工作的开展。

关 键 词:精神分裂症  证候要素  诊断量表  
收稿时间:2018-09-20

Establishing traditional Chinese medicine pattern elements diagnostic scale of schizophrenia
Yin Dongqing,Huang Fang,Zhao Anquan,Wang Qunsong,MA Yanbing,Chen Jindong,Li Baojun,Du Hong,Jia Hongxiao. Establishing traditional Chinese medicine pattern elements diagnostic scale of schizophrenia[J]. Journal of Capital Medical University, 2018, 39(6): 821-827. DOI: 10.3969/j.issn.1006-7795.2018.06.006
Authors:Yin Dongqing  Huang Fang  Zhao Anquan  Wang Qunsong  MA Yanbing  Chen Jindong  Li Baojun  Du Hong  Jia Hongxiao
Abstract:Objective To establish a traditional Chinese medicine (TCM) pattern element diagnostic scale of schizophrenia and promote the development of TCM syndrome standardization for schizophrenia. Methods The questionnaire of TCM pattern element of schizophrenia was designed, and TCM four diagnostic data from 302 schizophrenia cases were collected.The four diagnostic data were analyzed with occurrence frequency, the items of four diagnostic data with occurrence frequency>10% were retained. TCM pattern elements and the items of four diagnostic data were extracted based on factor analysis. Binary Logistic regression analysis was used to identify the items with different weight coefficient. Totally 302 schizophrenia cases were scored with these items. Then, TCM pattern elements diagnosed by TCM experts were set as variables(Y), the scores of TCM pattern elements obtained with the above items with different weight were set as variables (X), and diagnostic threshold was determined with receiver operating characteristic (ROC) curve. Results The TCM pattern element diagnostic scale for schizophrenia was established based on 302 schizophrenia cases.There were 10 pattern elements in the scale, including 8 TCM pattern elements of disease nature (fire-heat, Qi-deficiency, Qi-stagnation,Yin-deficiency, blood stasis,and Yang-deficiency) and 4 TCM pattern elements of disease location (Heart, Liver, Spleen, and Gallbladder). The total scale of every TCM pattern element diagnostic scale was 100, with diagnostic threshold as 60. Conclusion The establishment of TCM pattern elements diagnostic scale for schizophrenia will promote the standardization of TCM syndrome of schizophrenia.
Keywords:schizophrenia  TCM pattern elements  diagnostic scale  
点击此处可从《首都医科大学学报》浏览原始摘要信息
点击此处可从《首都医科大学学报》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号