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The distribution of anti-thyroglobulin antibodies in the immunoglobulin G subclasses |
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| Authors: | F C Hay G Torrigiani |
| Abstract: | Using the coprecipitation technique with rabbit antisera specific for the human IgG subclasses, the antigen–binding capacity for thyroglobulin has been investigated in patients with Hashimoto''s disease. Anti-thyroglobulin activity was found in all four subclasses. The proportion of the total activity in each subclass closely paralleled the relative amounts of each subclass in normal serum. |
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