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A novel treatment for keratitis sicca (Dry eye): Anatomical feasibility study
Authors:Joe Iwanaga  Koichi Watanabe  Jingo Kusukawa  Christian Fisahn  Fernando Alonso  Rod J. Oskouian  R. Shane Tubbs
Affiliation:1. Seattle Science Foundation, Seattle, Washington;2. Department of Anatomy, Kurume University School of Medicine, Kurume, Fukuoka, Japan;3. Dental and Oral Medical Center, Kurume University School of Medicine, Kurume, Fukuoka, Japan;4. Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington;5. Department of Anatomical Sciences, St. George's University, St. George's, Grenada
Abstract:Chronic dry eye (keratitis sicca) is a significant problem that in certain populations can result in corneal desiccation and the potential for blindness. Therefore, novel treatments for such disorders might decrease patient morbidity. The present study aimed to investigate a potential treatment for chronic dry eye via a cadaveric feasibility study. On 10 cadaveric sides, the parotid gland branch of the auriculotemporal nerve (ATN) was identified and anastomosed to an anterior superficial temporal branch (STb) of this same nerve. The STb was then transposed anteriorly and sutured to the lacrimal gland. The parotid branch of the ATN was easily identified on all sides. The STb of the ATN was easily identified and mobilized on all sides. This latter nerve had adequate length to be moved to the ipsilateral lacrimal gland on all sides. Rerouting parotid gland secretomotor fibers to the superficial branch of the ATN and then moving this branch to the lacrimal gland is a feasible surgical maneuver based on our cadaveric study. Clinical studies are now necessary to show utility of this procedure in patients with chronic dry eye. Clin. Anat. 30:839–843, 2017. © 2017Wiley Periodicals, Inc.
Keywords:keratitis sicca  dry eye syndrome  blindness  anatomy  lacrimal apparatus
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