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前哨淋巴结活检在早期乳腺癌患者腋窝管理中的研究进展
引用本文:梁良,曾福仁,杨虹,束永峰. 前哨淋巴结活检在早期乳腺癌患者腋窝管理中的研究进展[J]. 现代肿瘤医学, 2022, 0(3): 548-551. DOI: 10.3969/j.issn.1672-4992.2022.03.036
作者姓名:梁良  曾福仁  杨虹  束永峰
作者单位:1.湖南省人民医院(湖南师范大学附属第一医院)肿瘤科,湖南 长沙 410002;2.铜陵市中西医结合医院,安徽 铜陵 244000
摘    要:传统的观点认为腋窝淋巴结清扫(axillary lymph node dissection,ALND)是前哨淋巴结(sentinellymph node,SLN)阳性乳腺癌患者的标准治疗方法,而ALND容易引起上肢水肿、功能障碍等术后并发症,影响患者生活质量.近几年研究显示,对于SLN阳性的早期乳腺癌,并非所有患者都需...

关 键 词:乳腺肿瘤  前哨淋巴结活检  腋窝淋巴结清扫  肿瘤辅助疗法

Research progress of sentinel lymph node biopsy in axillary management for early breast cancer patients
LIANG Liang,ZENG Furen,YANG Hong,SHU Yongfeng. Research progress of sentinel lymph node biopsy in axillary management for early breast cancer patients[J]. Journal of Modern Oncology, 2022, 0(3): 548-551. DOI: 10.3969/j.issn.1672-4992.2022.03.036
Authors:LIANG Liang  ZENG Furen  YANG Hong  SHU Yongfeng
Affiliation:1.Department of Oncology,Hunan Provincial People's Hospital(the First Affiliated Hospital of Hunan Normal University),Hunan Changsha 410002,China;2.Tongling Integrated Chinese and Western Medicine Hospital,Anhui Tongling 244000,China.
Abstract:Traditionally,axillary lymph node dissection(ALND)is the standard treatment for patients with sentinel lymph node-positive breast cancer,while ALND tends to cause upper limb edema,dysfunction and other postoperative complications,which affect the quality of life of patients.Studies in recent years have shown that not all patients need ALND for SLN-positive early breast cancer.For early breast cancers patients who with micrometastasis and 1-2 SLN-positive,omitting ALND dose not affect overall survival.For breast cancer patients with positive clinical axillary lymph nodes,after the clinical axillary lymph nodes turn to the negative through neoadjuvant chemotherapy,whether SLNB can accurately assess the status of axillary lymph nodes is still controversial.This article will summarize the latest literature on breast cancer axillary treatment,and the therapeutic strategies for early breast cancer patients with positive sentinel lymph nodes and the clinical feasibility of SLNB after neoadjuvant chemotherapy for clinical lymph node positive breast cancer are reviewed.
Keywords:breast neoplasms  sentinel lymph node biopsy  axillary lymph node dissection  tumor adjuvant therapy
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