| 人参皂苷Rg3与离子通道受体作用的研究进展 |
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| 引用本文： | 冯晓娜,蒋 革,李铁福. 人参皂苷Rg3与离子通道受体作用的研究进展[J]. 沈阳药科大学学报, 2011, 28(10): 835-840 |
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| 作者姓名： | 冯晓娜 蒋 革 李铁福 |
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| 作者单位： | (1. 大连大学 生物工程学院，辽宁 大连 116600；2. 沈阳药科大学 制药工程学院，辽宁 沈阳 110016) |
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| 摘 要： | 目的对人参皂苷Rg3(ginsenoside Rg3,G-Rg3)与离子通道受体作用进行全面总结。方法根据国内外最新有关文献,依据作用的离子通道受体不同进行分类介绍。结果G-Rg3可作用于离子通道受体,通过与特定氨基酸残基的作用,影响离子通道活性,进而影响某些离子的通透性。结论为G-Rg3的药理作用研究提供参考。
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| 关 键 词： | 人参皂苷Rg3(G-Rg3) 离子通道受体 相互作用 |
| 收稿时间： | 2010-12-16 |
| 修稿时间： | 2011-07-01 |
Recent advances in ginsenoside Rg3 and ion channel receptors interactions |
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| FENG Xiao-na,JIANG Ge,LI Tie-fu. Recent advances in ginsenoside Rg3 and ion channel receptors interactions[J]. Journal of Shenyang Pharmaceutical University, 2011, 28(10): 835-840 |
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| Authors: | FENG Xiao-na JIANG Ge LI Tie-fu |
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| Affiliation: | FENG Xiao-na1,JIANG Ge1,LI Tie-fu2(1.Faculty of Bioscience Engineering,Dalian University,Dalian 116600,China,2.School of Pharmaceutical Engineering,Shenyang Pharmaceutical University,Shenyang 110016,China) |
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| Abstract: | Objective To summarize ginsenoside Rg3(G-Rg3) in ion channel receptors research comprehensively. Methods According to the latest relevant literature at home and abroad, the introduction by different categories of ion channel receptors interactions was summarized. Results G-Rg3 has an effect on ion channel receptors through the interaction with particular amino acid residues, thereby affecting the permeability of certain ions. Conclusions This will provide references for the pharmacological effects of G-Rg3. |
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| Keywords: | ginsenoside Rg3 (G-Rg3) ion channel receptor interaction |
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