| 纳米支架及合成技术在神经组织再生的应用 |
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| 引用本文： | 张震,李莹,耿亚伟,徐东阳,李德志,张斌. 纳米支架及合成技术在神经组织再生的应用[J]. 口腔医学研究, 2017, 33(4): 459. DOI: 10.13701/j.cnki.kqyxyj.2017.04.028 |
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| 作者姓名： | 张震 李莹 耿亚伟 徐东阳 李德志 张斌 |
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| 作者单位： | 1. 哈尔滨医科大学硬组织发育和再生研究所 黑龙江 哈尔滨 150001;2. 第二附属医院口腔修复科 黑龙江 哈尔滨 150001;3. 第二附属医院口腔颌面外科 黑龙江 哈尔滨 150001 |
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| 摘 要： | 神经系统受损常见于不同背景、年龄的人群。当前有许多促神经组织再生的方法,其中组织工程方法应用前景最为良好。采用组织工程技术合成的功能性神经支架,可用于代替、修复受损神经。组织工程技术合成的神经支架具有高度仿生性,且重建神经功能的成功率较高。尤其是纳米技术的应用,在很大程度上促进了神经组织工程技术的发展创新和成功运用。本文重点讨论采用纳米生物材料和生物活性物质以及静电纺丝技术、新出现的3D打印技术和自组装技术合成具有三维结构的纳米纤维神经支架来促进神经组织修复与再生研究进展。
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| 收稿时间： | 2015-11-17 |
Nanoscaffolds and Nanofabrication Techniques for Neural Tissue Regeneration. |
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| ZHANG Zhen,LI Ying,GENG Ya-wei,XU Dong-yang,LI De-zhi ZHANG Bin. Nanoscaffolds and Nanofabrication Techniques for Neural Tissue Regeneration.[J]. Journal of Oral Science Research, 2017, 33(4): 459. DOI: 10.13701/j.cnki.kqyxyj.2017.04.028 |
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| Authors: | ZHANG Zhen LI Ying GENG Ya-wei XU Dong-yang LI De-zhi ZHANG Bin |
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| Affiliation: | 1. Institute of Hard Tissue Development and Regeneration, Harbin Medical University. Harbin 15001, China; 2. Department of Prosthodontics, the Second Affiliated Hospital of Harbin Medical University. Harbin 15001, China; 3. Department of Oral and Maxillofacial Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin 15001, China. |
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| Abstract: | Tissue engineering is the promising avenue to improve neural regeneration. Functional nerve scaffolds synthesized by tissue engineering techniques present substitutes for implantation and rehabilitation of injured nerves. The scaffolds have a high degree of biomimetic and a superior rate of successful neural function construction. Particularly, the application of nanotechnology has greatly promoted the development of neural tissue engineering technology and the successful application of the technology. In this paper, we focus on the development of nano-scaffold and nanotechonlogy on the nerve tissue repair and regeneration of the nerve tissue, which is synthesized by the nano material and the biological active material, the electrospinning technology, the new 3D printing technology, and the self assembly technology. |
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| Keywords: | Neural tissue-engineering Nanotechnology Scaffold Electrospinning 3D printingSelf-assembly |
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