| Effect of Shuxinyin (舒心饮) on In-Stent Restenosis after Coronary Artery Stenting |
| |
| 引用本文： | 王显,林钟香,葛均波,刘旭,何燕,张振贤,沈琳. Effect of Shuxinyin (舒心饮) on In-Stent Restenosis after Coronary Artery Stenting[J]. 中国结合医学杂志, 2002, 8(3) |
| |
| 作者姓名： | 王显 林钟香 葛均波 刘旭 何燕 张振贤 沈琳 |
| |
| 作者单位： | 王显(Department of Cardiology,.Beijing Hospital of Integrated Traditional and Western Medicine,Beijing,100039);林钟香,何燕,张振贤,沈琳(Long-hua Hospital Affiliated to Shanghai TCM University);葛均波(Zhongs-han Hospital Affiliated to Fudan University);刘旭(Shanghai Chest Hospital) |
| |
| 基金项目： | CollegeFoundationofShanghaiEducationalCommittee(99C6 6 ) |
| |
| 摘 要： | Objective: To evaluate the effect of anti-platelet regimens and it's combination with Shuxinyin (SXY, 舒心饮,) on in-stent restenosis after stent implantation. Methods: Forty-four patients with successful stent implantation in a coronary artery were randomly assigned to the treated group (n=20) and the control group (n=24). The treated group received: SXY and anti-platelet therapy. The control group were treated with anti-platelet regimens only. Platelet activation was assessed before and immediately after the stenting by flow cytometry, the expression of P-selectin (CD62P) and glycoprotein(GP) Ⅱb/Ⅲa receptor. It was reassessed on the 30th day after stenting. Plasma fibrinogen (Fg) and C-reaction protein (CRP) were measured by biuret and laser scattering turbidimetry respectively at the same time. Observation was made on the scoring of the symptoms of Qi deficiency syndrome, Qi-Yin deficiency syndrome and blood stasis syndrome in the two groups. Differences between groups were compared. Results: Compared with the control group, combination with SXY and anti-platelet therapy was remarkable in reducing plasma CRP (P<0.05), and also with the tendency to decrease plasma Fg, GPⅡb/Ⅲa and CD62P. It could also evidently decrease the scoring of Qi-Yin deficiency syndrome, Qi deficiency syndrome and blood stasis syndrome after stenting (P<0.05, 0.01, 0.01) respectively. Follow-up survey found 40% relapse of angina pectoris with 4 cases of in-stent restenosis proved by angiography in the treated group. But the relapse of angina pectoris in the control group was 67% with 2 cases of myocardial infarction (MI), 7 cases of in-stent restenosis proved by angiography and one death. Conclusions: Combination with SXY and anti-platelet regimens can prevent stent thrombosis and in-stent restenosis after stent implantation, and it seems superior to anti-platelet therapy only.
|
Effect of Shuxinyin (舒心饮) on In-Stent Restenosis after Coronary Artery Stenting |
| |
| Abstract: | |
| |
| Keywords: | angioplasty stenting in-stent restenosis platelets glycoprotein Shuxinyin |
| 本文献已被 万方数据 等数据库收录！ |
|
