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Postoperative wound dehiscence: Predictors and associations
Authors:Victoria K. Shanmugam MD  MRCP  Stephen J. Fernandez MPH  Karen Kim Evans MD  Sean McNish MS  CRA  Anirban N. Banerjee PhD  Kara S. Couch MS  CRNP   CWS  Mihriye Mete PhD  Nawar Shara PhD
Affiliation:1. Division of Rheumatology, Wound Healing and Limb Preservation Center, Ideas to Health Laboratory, The George Washington University, School of Medicine and Health Sciences, Washington, DC;2. Department of Biostatistics and Bioinformatics, MedStar Health Research Institute, Georgetown‐Howard Universities Center for Clinical and Translational Science, Hyattsville, Maryland;3. Center for Wound Healing, MedStar Georgetown University Hospital, Washington, DC
Abstract:The Agency for Healthcare Research and Quality patient safety indicators (PSI) were developed as a metric of hospital complication rates. PSI‐14 measures postoperative wound dehiscence and specifically how often a surgical wound in the abdominal or pelvic area fails to heal after abdominopelvic surgery. Wound dehiscence is estimated to occur in 0.5–3.4% of abdominopelvic surgeries, and carries a mortality of up to 40%. Postoperative wound dehiscence has been adopted as a surrogate safety outcome measure as it impacts morbidity, length of stay, healthcare costs and readmission rates. Postoperative wound dehiscence cases from the Nationwide Inpatient Sample demonstrate 9.6% excess mortality, 9.4 days of excess hospitalization and $40,323 in excess hospital charges relative to matched controls. The purpose of the current study was to investigate the associations between PSI‐14 and measurable medical and surgical comorbidities using the Explorys technology platform to query electronic health record data from a large hospital system serving a diverse patient population in the Washington, DC and Baltimore, MD metropolitan areas. The study population included 25,636 eligible patients who had undergone abdominopelvic surgery between January 1, 2008 and December 31, 2012. Of these cases, 786 (2.97%) had postoperative wound dehiscence. Patient‐associated comorbidities were strongly associated with PSI‐14, suggesting that this indicator may not solely be an indicator of hospital safety. There was a strong association between PSI‐14 and opioid use after surgery and this finding merits further investigation.
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