| 芜湖市临产孕妇弓形虫感染率及垂直传播率的研究 |
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| 引用本文： | 奚旭霞,蒋峰. 芜湖市临产孕妇弓形虫感染率及垂直传播率的研究[J]. 中国血吸虫病防治杂志, 2019, 31(6): 658 |
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| 作者姓名： | 奚旭霞 蒋峰 |
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| 作者单位： | 1 安徽省芜湖市第一人民医院妇产科（芜湖 241002）;2 皖南医学院医学寄生虫学教研室 |
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| 基金项目： | 安徽省芜湖市科技计划项目（2015hm14） |
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| 摘 要： | 目的 探讨芜湖市临产孕妇弓形虫感染率及垂直传播率,为芜湖地区孕妇弓形虫病防治提供参考。方法 采集芜湖市临产孕妇静脉血及新生儿足后跟血液,制成滤纸血片样本,应用环介导等温扩增技术检测临产孕妇弓形虫感染率及垂直传播率。结果 475例临产孕妇共检出阳性样本3例,平均阳性检出率为0.63%,其中< 20周岁孕妇（0/5）和高龄孕妇（0/24）阳性感染率均为0,适龄孕妇阳性感染率为0.67%（3/446）。新生儿检出阳性样本2例,垂直传播率为66.67%。结论 芜湖市临产孕妇存在弓形虫感染,且垂直传播率较高;孕妇应努力提高对弓形虫病潜在危险因素的认识,预防因弓形虫病带来的危害。
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| 关 键 词： | 刚地弓形虫 环介导等温扩增 垂直传播 临产孕妇 芜湖市 |
Study on prevalence and vertical transmission rate of Toxoplasma gondii infections among parturient women in Wuhu City |
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| XI Xu-Xia,JIANG Feng. Study on prevalence and vertical transmission rate of Toxoplasma gondii infections among parturient women in Wuhu City[J]. Chinese journal of schistosomiasis control, 2019, 31(6): 658 |
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| Authors: | XI Xu-Xia JIANG Feng |
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| Affiliation: | 1 Department of Obstetrics and Gynecology, The First People’s Hospital of Wuhu, Wuhu 241002, China; 2 Department of Medical Parasitology, Wannan Medical College, China |
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| Abstract: | Objective To investigate the prevalence and vertical transmission rate of Toxoplasma gondii infections among in parturient women in Wuhu City, so as to provide reference for the prevention and control of toxoplasmosis among pregnant women in the city. Methods Parturient women’s venous blood samples and neonatal heel blood samples were collected in Wuhu City and prepared into filter?paper blood samples. The prevalence and vertical transmission rate of T. gondii infections were detected using the loop?mediated isothermal amplification (LAMP) assay among the parturient women. Results There were three positive samples detected in the 475 filter?paper blood samples from the parturient women, with a mean positive rate of 0.63%. The prevalence of T. gondii infection was 0 in pregnant women at ages of < 20 years (0/5) and at an advanced maternal age (0/24), while the prevalence was 0.67% (3/446) in pregnant women at an appropriate maternal age. T. gondii infection was detected in 2 filter?paper blood samples from newborns, with a vertical transmission rate of 66.67%. Conclusions There is T. gondii infection in the parturient women and a high vertical transmission rate of T. gondii infection is detected in Wuhu City. The awareness of the potential risk factors of toxoplasmosis should be improved among pregnant women to prevent the damages of toxoplasmosis to humans. |
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| Keywords: | Toxoplasma gondii Loop?mediated isothermal amplification Vertical transmission Parturient woman Wuhu City |
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