Immunologic Paradox in the Diagnosis of Tuberculous Meningitis |
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| Authors: | Sung-Han Kim Yang Soo Kim |
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| Affiliation: | Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea |
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| Abstract: | We report a patient with microbiologically documented tuberculous meningitis showing that the therapeutic paradox, a therapy-induced switch to a neutrophil-predominant situation in the differential cell counts of cerebrospinal fluid specimens, had a correlation with an immunologic paradox, an increased Mycobacterium tuberculosis-specific gamma interferon-producing T-cell response. |
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