| 结直肠癌腹主动脉旁淋巴结转移的研究进展 |
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| 引用本文： | 吴迪,殷红专,苏琪. 结直肠癌腹主动脉旁淋巴结转移的研究进展[J]. 中国肿瘤临床, 2022, 49(4): 201-205. DOI: 10.12354/j.issn.1000-8179.2022.20210251 |
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| 作者姓名： | 吴迪 殷红专 苏琪 |
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| 作者单位： | 中国医科大学附属盛京医院普外科，结直肠肛门病外科病房 （沈阳市110004） |
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| 摘 要： | 淋巴结转移是影响结直肠癌预后的重要因素之一。结直肠癌腹主动脉旁淋巴结转移（para-aortic lymph node metastasis，PALNM）是结直肠癌不常见的转移模式。由于其发病率相比肝转移和肺转移低，相关的研究均存在一定的局限性，因此对于结直肠癌PALNM的诊断及治疗尚存争议。腹主动脉旁淋巴结清扫（para-aortic lymph node dissection，PALND）术可以为判断腹主动脉旁淋巴结有无转移提供病理依据，也可以改善部分患者的预后。虽然对于结直肠癌肝转移和（或）肺转移进行积极的手术切除已经得到普遍认同，但对于结直肠癌合并PALNM的最佳手术治疗策略仍未明确。是否进行PALND，需要权衡其安全性、有效性、复发率与其所带来的生存获益之间的关系。本文将就有关结直肠癌PALNM的研究治疗进展进行综述。
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| 关 键 词： | 结直肠肿瘤 转移 腹主动脉旁淋巴结转移 腹主动脉旁淋巴结清扫术 |
| 收稿时间： | 2021-02-02 |
Research progress of para-aortic lymph node metastasis in colorectal cancer |
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| Affiliation: | Colorectal and Anal Disease Surgery Ward, Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China |
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| Abstract: | Lymph node involvement is one of the most important prognostic factors for colorectal cancer. Para-aortic lymph node metastasis (PALNM) is an uncommon mode of metastasis of colorectal cancer. Because the incidence of colorectal cancer is lower than that of liver and lung metastases, related studies have certain limitations. Therefore, the diagnosis and treatment of PALNM in colorectal cancer are unclear. Para-aortic lymph node dissection (PALND) can provide a pathological diagnosis and can also improve the prognosis of some selected patients. Although aggressive surgical resection of colorectal cancer with liver and lung metastases is indicated, the optimal surgical management strategy for colorectal cancer with PALNM remains unclear. To determine whether PALND should be performed, the relationship between its safety, effectiveness, recurrence rate, and survival benefit needs to be assessed. This study reviews the research and treatment progress of PALNM in colorectal cancer in recent years. |
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