Tsukamurella inchonensis infection in a child with Hodgkin's lymphoma |
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Authors: | Fumihiro Ochi Hisamichi Tauchi Kyoko Moritani Hitoshi Miyamoto Kiyofumi Ohkusu Eiichi Ishii |
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Affiliation: | 1. Department of Pediatrics, Ehime University Graduate School of Medicine, Ehime, Japan;2. Division of Clinical Laboratory, Ehime University Hospital, Ehime, Japan;3. Department of Microbiology, Regeneration and Advanced Medical Science, Gifu University School of Medicine, Gifu, Japan |
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Abstract: | Tsukamurella spp. infection is a rare but important cause of bacteremia in immunocompromised patients. The organism is an aerobic, Gram‐positive, weakly acid‐fast bacillus that is difficult to differentiate from other aerobic Actinomycetales by standard laboratory methods. Here, we report on the case of a 14‐year‐old patient with Hodgkin's lymphoma who, after intensive chemotherapy, developed Tsukamurella inchonensis bacteremia, which was identified on the peripherally inserted central venous catheter (PICC) using 16S rRNA sequencing analysis. The bacteremia was successfully controlled with antimicrobial therapy and subsequent removal of the PICC. This is the first report of bacteremia by Tsukamurella inchonensis in immunocompromised children. Careful observation and prompt analysis of opportunistic infection, including Tsukamurella spp., is very important in immunocompromised children. |
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Keywords: | bacteremia catheter‐related bloodstream infection central venous catheters Hodgkin's lymphoma Tsukamurella inchonensis |
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