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Tsukamurella inchonensis infection in a child with Hodgkin's lymphoma
Authors:Fumihiro Ochi  Hisamichi Tauchi  Kyoko Moritani  Hitoshi Miyamoto  Kiyofumi Ohkusu  Eiichi Ishii
Affiliation:1. Department of Pediatrics, Ehime University Graduate School of Medicine, Ehime, Japan;2. Division of Clinical Laboratory, Ehime University Hospital, Ehime, Japan;3. Department of Microbiology, Regeneration and Advanced Medical Science, Gifu University School of Medicine, Gifu, Japan
Abstract:Tsukamurella spp. infection is a rare but important cause of bacteremia in immunocompromised patients. The organism is an aerobic, Gram‐positive, weakly acid‐fast bacillus that is difficult to differentiate from other aerobic Actinomycetales by standard laboratory methods. Here, we report on the case of a 14‐year‐old patient with Hodgkin's lymphoma who, after intensive chemotherapy, developed Tsukamurella inchonensis bacteremia, which was identified on the peripherally inserted central venous catheter (PICC) using 16S rRNA sequencing analysis. The bacteremia was successfully controlled with antimicrobial therapy and subsequent removal of the PICC. This is the first report of bacteremia by Tsukamurella inchonensis in immunocompromised children. Careful observation and prompt analysis of opportunistic infection, including Tsukamurella spp., is very important in immunocompromised children.
Keywords:bacteremia  catheter‐related bloodstream infection  central venous catheters  Hodgkin's lymphoma  Tsukamurella inchonensis
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