Liver transplantation as a definitive treatment for familial hypercholesterolemia: A series of 36 cases |
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| Authors: | Mohsenreza Mansoorian Kourosh Kazemi Saman Nikeghbalian Alireza Shamsaeefar Maral Mokhtari Seyed Mohsen Dehghani Ali Bahador Heshmatollah Salahi Hamid Amoozgar Seyed Ali Malek Hosseini |
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| Affiliation: | 1. Surgery Department, Transplant Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran;2. Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran;3. Pediatric Gastroenterology and Hepatology Department, Shiraz University of Medical Sciences, Shiraz, Iran;4. Cardiac and Neonatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran |
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| Abstract: | FH is a genetic disorder characterized by an increase in serum LDL and total cholesterol values. The afflicted patients are at increased risk of premature atherosclerosis and myocardial infarction. Different treatment modalities are present, including pharmacological agents and surgical procedures. The most effective method of therapy in refractive cases is liver transplantation. Herein, we report our experience on 36 cases of patients with FH undergoing liver transplantation in our center, the main referral center of liver transplantation in Iran. The clinical findings, hospital courses, post‐operative complications, and patient follow‐up are also described. |
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| Keywords: | familial hypercholesterolemia liver transplantation |
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