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IL‐6, IL‐8, MMP‐2, MMP‐9 are overexpressed in Fanconi anemia cells through a NF‐κB/TNF‐α dependent mechanism
Authors:Alexey Epanchintsev  Pavithra Shyamsunder  Rama S. Verma  Alex Lyakhovich
Affiliation:1. Institute of Genetics and Molecular and Cellular Biology, Department of Functional Genomics and Cancer Biology, Centre National de la Recherche Scientifique/Institut National de la Santé et de la Recherche Médicale Illkirch Cedex, France;2. Department of Biotechnology, Stem Cell and Molecular Biology Laboratory, Indian Institute of Technology Madras, Chennai, India;3. Novosibirsk Institute of Molecular Biology and Biophysics, Novosibirsk, Russia;4. Cancer & Stem Cell Biology Program, Duke‐NUS Graduate Medical School, Singapore, Singapore;5. Queen's University Belfast, Belfast, UK
Abstract:
Keywords:Fanconi anemia  interleukins  metalloproteinases  EMT  cancer micro‐environment
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