| 氦氖激光对心肌梗死大鼠血清自由基影响 |
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| 引用本文： | 杨颖, 张杰梅, 庞东卫, 徐洋. 氦氖激光对心肌梗死大鼠血清自由基影响[J]. 中国公共卫生, 2008, 24(7): 824-825. DOI: 10.11847/zgggws2008-24-07-30 |
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| 作者姓名： | 杨颖 张杰梅 庞东卫 徐洋 |
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| 作者单位： | 1.包头医学院物理教研室, 内蒙古包头014010;2.包头医学院第一附属医院心内科;3.包头医学院生理教研室;4.包头医学院第一附属医院物理诊断科 |
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| 摘 要： | 目的探讨氦氖激光对心肌梗死大鼠血清中超氧化物歧化酶(SOD)、丙二醛(MDA)和一氧化氮(NO)的影响。方法以特定的氦氖激光强度、经不同的照射时间照射心肌梗死大鼠心前区,观察血清自由基水平的改变。结果氦氖激光照射心肌梗死大鼠心前区10和20min时血清中SOD升高(48.86,50.22 U/ml),与对照组比较(44.28U/ml),差异有统计学意义(P<0.05);MDA降低(3.94,3.99 nmol/L),与对照组比较(4.78nmol/L),差异有统计学意义(P<0.05);照射20min时血清中NO升高(388.86μmol/L),与对照组比较(286.46μmol/L),差异有统计学意义(P<0.05)。结论氦氖激光照射心前区对于冠心病、心肌缺血的治疗有一定意义。
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| 关 键 词： | 氦氖激光 心肌梗死 心前区 自由基 |
| 收稿时间： | 2007-10-16 |
Effect of He-Ne laser on serum free radicals in rats with myocardial infarction |
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| YANG Ying, ZHANG Jie-mei, PANG Dong-wei, . Effect of He-Ne laser on serum free radicals in rats with myocardial infarction[J]. Chinese Journal of Public Health, 2008, 24(7): 824-825. DOI: 10.11847/zgggws2008-24-07-30 |
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| Authors: | YANG Ying ZHANG Jie-mei PANG Dong-wei |
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| Affiliation: | 1.Department of Physics, Baotou Medical College, Baotou 014010, China |
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| Abstract: | ObjectiveTo probe into the effect of He-Ne laser on superoxide dismutase(SOD),malon-dialdehyde (MDA)and nitric oxide(NO)in the serum of the rats with myocar dial infarction.MethodsThe myocardial infarcted rats were ir adiated on their precordial regions by HE-Ne laser with certain intensity for different time to observe changes of serum free radical levels.ResultsCompared with the control group(44.28U/ml),the content of SODin myocar dial infarcted rats irridiated by He-Ne laser for 10 and 20 min increased significantly(48.86,50.22 U/ml,P<0.05).Compared with the control group(4.78 nmol/L),the content of serum MDA decreased significantly(3.94,3.99 nmol/L,P<0.05).By 20min irradiating,compared with the control group(286.46μmol/L),the content of NO in rats.serum increased significantly (388.86μmol/L,P<0.05).ConclusionHe-Ne laser irradiation on the precordial region has certain significance in treating coronary heart disease and myocardial ischemia. |
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| Keywords: | He-Ne laser myocardial infar ction precordia region free radical |
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