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溃疡性结肠炎患者血清降钙素原检测分析
引用本文:杨旭光,谢扬,韩溟. 溃疡性结肠炎患者血清降钙素原检测分析[J]. 现代临床医学, 2012, 38(2): 103-104. DOI: 10.3969/j.issn.1673-1557.2012.02.011
作者姓名:杨旭光  谢扬  韩溟
作者单位:1.揭西县中医院,广东揭阳,515400;2.汕头大学医学院第二附属医院,广东汕头,515041
摘    要:目的:探讨检测血清降钙素原(PCT)水平在溃疡性结肠炎(UC)的临床意义.方法:采用ELISA法检测64例UC活动期患者和35例缓解期患者外周血PCT水平及血中性粒细胞计数.结果:UC活动期患者血中性粒细胞计数及PCT水平显著高于正常对照组(P<0.05),PCT水平在活动期也显著高于缓解期(P<0.05),PCT水平随活动期病情严重程度的加重而升高.结论:血清PCT水平可能作为评价UC患者病情活动及严重程度的辅助指标.

关 键 词:降钙素原  溃疡性结肠炎  诊断

Clinical Significance of Serum Procalcitonin in the Patients with Ulcerative Colitis
YANG Xu-guang,XIE Yang and HAN Ming. Clinical Significance of Serum Procalcitonin in the Patients with Ulcerative Colitis[J]. Journal of Modern Clinical Medicine, 2012, 38(2): 103-104. DOI: 10.3969/j.issn.1673-1557.2012.02.011
Authors:YANG Xu-guang  XIE Yang  HAN Ming
Affiliation:1.Jiexi TCM Hospital,Guangdong Jieyang 515400,China; 2.The Second Affiliated Hospital of Shantou University Medical College,Guangdong Shantou 515041,China)
Abstract:Objective:To evaluate the clinical significance of serum procalcitonin(PCT) in patients with ulcerative colitis(UC).Methods:Enzyme linked immunosorbent assay(ELISA) was used to determine the level of serum PCT in 64 patients with active phase of UC,35 patients with catabasis UC.In addition,the number of neutrophils in blood was recorded.Results:The level of PCT in patients with active phase UC were significantly higher than that of patients with catabasis UC and healthy controls(P<0.05).The number of blood neutrohpils were significantly higher in patients with UC than those of healthy controls(P<0.05).In addition,PCT level was correlated with the severity of disease.Conclusion:Serum PCT level may be a potential marker in the evaluation of UC severity.
Keywords:procalcitonin  ulcerative colitis  diagnosis
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