| 临床腋淋巴结阴性乳腺癌前哨淋巴结研究 |
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| 引用本文： | 王永胜,王磊,刘娟娟,左文述,于志勇,刘岩松,李永清,刘雁冰. 临床腋淋巴结阴性乳腺癌前哨淋巴结研究[J]. 外科理论与实践, 2001, 6(4): 206-209. DOI: 10.16139/j.1007-9610.a0553 |
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| 作者姓名： | 王永胜 王磊 刘娟娟 左文述 于志勇 刘岩松 李永清 刘雁冰 |
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| 作者单位： | 山东省肿瘤防治研究院山东省乳腺病防治中心!(250117),山东省肿瘤防治研究院山东省乳腺病防治中心!(250117),山东省肿瘤防治研究院山东省乳腺病防治中心!(250117),山东省肿瘤防治研究院山东省乳腺病防治中心!(250117),山东省肿瘤防治研究院山东省乳腺病防治中心!(250117),山东? |
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| 基金项目： | 山东省科技厅计划项目(003130139);山东省人事厅留学归国人员资助项目. |
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| 摘 要： | 目的：探讨前哨淋巴结活检术（ｓｅｎｔｉｎｅｌ ｌｙｍｐｈ ｎｏｄｅ ｂｉｏｐｓｙ， ＳＬＮＢ）在乳腺癌治疗中的应用。方法：使用专利蓝和美蓝染色，对１９９９年９月～２００１年４月连续收治的１４５例临床查体腋窝淋巴结阴性乳腺癌病人行前哨淋巴结活检术。结果：ＳＬＮＢ成功率为９６．５％（１４０／１４５），假阴性率为２３．５％，准确率为９１．４％。病人年龄、肿瘤最大径、肿瘤部位、注射染料类型及是否活检对成功率和假阴性率无影响。结论：ＳＬＮＢ能够准确预测腋窝淋巴结的转移状况，在缩小手术范围、减少术后并发症的同时，提高了腋窝淋巴结分期的准确性；美蓝与专利蓝均可成功确定ＳＬＮ。
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| 关 键 词： | 乳腺癌 外科手术 前哨淋巴结 |
| 修稿时间： | 2001-04-27 |
Study of Sentinel Lymph Node Biopsy in Clinical Lymph Node Negative Breast Cancer |
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| Abstract: | Objective: To study the role of sentinel lymph node biopsy(SLNB)in clinical node negative breast cancer. Methods: From Sep. 1999 to Apr. 2001, sentinel lymph node biopsy(SLNB) by using patent blue V or methylthionium stain were performed to 145 patients with clinical axillary node negative breast cancer. Results: SLN were successfully identified in 140 of 145 (96.5%) patients. The accuracy rate of SLNB to predict axillary lymph node status was 91.4% (128/140), with 23.5% false negative rate. No sig- nificant correlation was found between successful identification of SLN or false negative results and the tumor size, location, pathologic type, patients' age, the type of dye or prior biopsy.Con- clusions: SLNB could accurately predict the axillary status of clinical negative node, improve the ac- curacy of the axillary staging and decrease the extent of surgery and postoperative complication in pa- tients with breast cancer. Methylthionium can produce the same effect in identifying SLN as patent blue V. |
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| Keywords: | Breast cancer Surgery Sentinel lymph node |
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