| 产科抗磷脂综合征的诊断和治疗 |
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| 引用本文： | 刘平,樊尚荣. 产科抗磷脂综合征的诊断和治疗[J]. 中华产科急救电子杂志, 2019, 8(2): 87-92. DOI: 10.3877/cma.j.issn.2095-3259.2019.02.006 |
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| 作者姓名： | 刘平 樊尚荣 |
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| 作者单位： | 1. 518036 深圳，北京大学深圳医院妇产科 |
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| 基金项目： | 深圳市科创委基础研究项目(JCYJ20160428175005906) |
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| 摘 要： | 产科抗磷脂综合征可导致早期复发性流产、死胎、胎盘功能不全和子痫前期等。小剂量阿司匹林和低分子量肝素为一线治疗方案，但仍有30%的病例治疗失败。难治性产科抗磷脂综合征、灾难性抗磷脂综合征的治疗可以使用羟基氯喹、糖皮质激素、静脉免疫球蛋白和血浆置换。抗磷脂综合征妊娠已成为产科研究的一个重要领域，新的治疗方法不断出现。
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| 关 键 词： | 抗磷脂综合征 妊娠并发症 |
| 收稿时间： | 2019-01-28 |
Diagnosis and management of obstetric antiphospholipid syndrome |
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| Ping Liu,Shangrong Fan. Diagnosis and management of obstetric antiphospholipid syndrome[J]. Chinese Journal of Obstetric Emergency (Electronic Edition), 2019, 8(2): 87-92. DOI: 10.3877/cma.j.issn.2095-3259.2019.02.006 |
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| Authors: | Ping Liu Shangrong Fan |
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| Abstract: | Obstetric antiphospholipid syndrome can lead to early recurrent miscarriage, stillbirth, placental insufficiency and preeclampsia. Low-dose aspirin and low-molecular-weight heparin are first-line treatment options, but 30% of cases still fail. Refractory obstetric antiphospholipid syndrome, catastrophic antiphospholipid syndrome patients can be treated with hydroxychloroquine, glucocorticoid, intravenous immunoglobulin and plasma exchange. Pregnancy with antiphospholipid syndrome has become an important area of obstetric research, and new treatments are emerging. |
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| Keywords: | Antiphospholipid syndrome Pregnancy complications |
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