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糖尿病周围神经病相关发病机制研究进展
引用本文:黄海伦,吴珊. 糖尿病周围神经病相关发病机制研究进展[J]. 中华脑科疾病与康复杂志(电子版), 2019, 9(3): 176-180. DOI: 10.3877/cma.j.issn.2095-123X.2019.03.012
作者姓名:黄海伦  吴珊
作者单位:1. 550004 贵阳,贵州医科大学神经病学教研室2. 550004 贵阳,贵州医科大学附属医院神经内科
基金项目:贵州省科技合作计划项目(黔科合LH字(2015)7407)
摘    要:糖尿病周围神经病(DPN)作为糖尿病最常见的并发症,一定程度上表现为周围神经功能障碍,影响患者的生活质量。基于近年来国内外对DPN相关发病机制的研究,本文主要围绕DPN在代谢、免疫、基因、降糖药等方面的相关发病机制展开综述,为今后DPN的机制研究与治疗提供思路。

关 键 词:糖尿病周围神经病  发病机制  免疫  遗传  降糖药物  
收稿时间:2019-05-19

Research progress on the pathogenesis of diabetic peripheral neuropathy
Hailun Huang,Shan Wu. Research progress on the pathogenesis of diabetic peripheral neuropathy[J]. The Chinese brain disease and rehabilitation magazine (electronic version), 2019, 9(3): 176-180. DOI: 10.3877/cma.j.issn.2095-123X.2019.03.012
Authors:Hailun Huang  Shan Wu
Affiliation:1. Department of Neurology, Guizhou Medical University, Guiyang 550004, China2. Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China
Abstract:Diabetic peripheral neuropathy (DPN), as the most common complication of diabetes mellitus, is manifested in peripheral nerve dysfunction to a certain extent, affecting the quality of life of patients. Based on the research on the pathogenesis of DPN at home and abroad in recent years, this paper reviews the pathogenesis of DPN in the aspects of metabolism, immunity, genes and hypoglycemic drugs, so as to provide ideas for the research and treatment of DPN mechanism in the future.
Keywords:Diabetic peripheral neuropathy  Pathogenesis  Immunity  Genetics  Hypoglycemic drugs  
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