| 盐酸戊乙奎醚治疗有机磷中毒疗效观察 |
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| 引用本文： | 赵清齐,张会. 盐酸戊乙奎醚治疗有机磷中毒疗效观察[J]. 新乡医学院学报, 2009, 26(6): 599-601 |
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| 作者姓名： | 赵清齐 张会 |
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| 作者单位： | 新乡市第一人民医院急诊科 |
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| 摘 要： | 目的观察盐酸戊乙奎醚救治有机磷中毒的临床效果。方法62例有机磷中毒患者分为2组,盐酸戊乙奎醚组32例采用盐酸戊乙奎醚进行治疗,阿托品组30例采用传统阿托品治疗,并对2组治疗效果进行比较。结果盐酸戊乙奎醚组的抢救成功率明显高于阿托品组(P<0.05),用药次数少于阿托品组(P<0.05),胆碱酯酶恢复时间、症状消失时间、昏迷时间以及机械通气时间明显短于阿托品组(P<0.05)。结论盐酸戊乙奎醚可明显减轻中毒患者早期的呼吸抑制,减少患者机械通气时间,是治疗有机磷中毒,特别是伴发呼吸衰竭患者的有效药物。
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| 关 键 词： | 盐酸戊乙奎醚 阿托品 有机磷中毒 |
Effect of penehyclidine hydrochloride on patients with organophosphate poisoning |
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| ZHAO Qing-qi,ZHANG Hui. Effect of penehyclidine hydrochloride on patients with organophosphate poisoning[J]. Journal of Xinxiang Medical College, 2009, 26(6): 599-601 |
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| Authors: | ZHAO Qing-qi ZHANG Hui |
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| Affiliation: | Department of Emergency，the First people′s Hospital of Xinxiang City，Xinxiang 453000，China |
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| Abstract: | Objective To observe the effect of penehyclidine hydrochloride on patients with organophosphate poisoning. Methods Sixty-two patients with organophosphate poisoning were divided into penehyelidine hydrochloride group （32 cases ） and atropine group（30 eases）. The curative effect was compared between two groups. Results Compared with atropine group, the achievement ratio of salvage was higher（ P 〈 0.05 ）, the time of medication was minor（ P 〈 0.05 ）, the coincidnece time of cholinesterase, extinction time of symptom, exanimation time and the time of mechanical ventilation were shorter in penehyclidine hydrochloride group （ P 〈 0. 05 ）. Conclusion Penehyclidine hydrochloride is active drug to treat the patients with organophosphate poisoning,it can lessen respiratory depression, and shorten the time of mechanical ventilation. |
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| Keywords: | penehyclidine hydrochloride atropine organophosphate poisoning |
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